11 Result(s)
-
Article
Open AccessMolecular alterations and prognosis of breast cancer with cutaneous metastasis
Cutaneous metastasis (CM) accounts for 5–30% of patients with breast cancer (BC) and presents unfavorable response to treatment and poor prognosis. A better understanding of the molecular alterations involved ...
-
Article
Open AccessSPAG5 deficiency activates autophagy to reduce atherosclerotic plaque formation in ApoE−/− mice
Autophagy, as a regulator of cell survival, plays an important role in atherosclerosis (AS). Sperm associated antigen 5 (SPAG5) is closely associated with the classical autophagy pathway, PI3K/Akt/mTOR signali...
-
Article
Open AccessChanges in the epidemiology and clinical characteristics of viral gastroenteritis among hospitalized children in the Mainland of China: a retrospective study from 2016 to 2020
Acute gastroenteritis (AGE) causes significant morbidity in children worldwide; however, the disease burden of children hospitalized with viral gastroenteritis in China has been rarely described. Through this ...
-
Article
Open AccessAssociation of serum uric acid with anemia in U.S. adults: a cross-sectional study using secondary data
High serum uric acid (SUA) is a risk factor of cardiovascular disease (CVD). Abnormal SUA have been correlated with a significant increase in mortality. Anemia is an independent predictor of mortality and CVD....
-
Article
Open AccessClinical characteristics of central nervous system candidiasis due to Candida albicans in children: a single-center experience
Central nervous system candidiasis due to Candida albicans (CNSC) in children is easily misdiagnosed and is associated with poor outcomes and a high mortality rate. There is no big data research or systematic rev...
-
Article
Vaccinia-related kinase 2 drives pancreatic cancer progression by protecting Plk1 from Chfr-mediated degradation
As a key cell cycle regulator, polo-like kinase 1 (Plk1) has been recognized as a crucial factor involved in the progression of pancreatic cancer (PC). However, its regulatory mechanism is poorly understood. H...
-
Article
Open AccessClinical characteristics of COVID-19 complicated with pleural effusion
Epidemiological and clinical features of patients with corona virus disease 2019 (COVID-19) were well delineated. However, no researches described the patients complicated with pleural effusion (PE). In the pr...
-
Article
Open AccessRisk factors of embolism for the cardiac myxoma patients: a systematic review and metanalysis
The risk factors contributing to embolism in cardiac myxoma (CM) are yet controversial. This systematic review and meta-analysis aimed to clarify the risk factors of embolism for the CM patients.
-
Article
Open AccessEvaluation of the anti-cancer potential of Cedrus deodara total lignans by inducing apoptosis of A549 cells
Cedrus deodara (Roxb.) Loud (normally called as deodar), one out of four species in the genus Cedrus, exhibits widely biological activities. The Cedrus deodara total lignans from the pine needles (CTL) were extra...
-
Article
Clinical characteristics and prognosis of pediatric cryptococcosis in Bei**g Children’s Hospital, 2002–2014
Cryptococcosis is a rare pediatric disease. The aim of the study is to describe clinical characteristics and prognosis of pediatric cryptococcosis from 2002 to 2014 in Bei**g Children’s Hospital. A total of 5...
-
Article
Association analysis of ERCC5 gene polymorphisms with risk of breast cancer in Han women of northwest China
ERCC5 plays an important role in DNA damage repair. Mutations in it will lead to DNA repair defects and genomic instability. Its functional single nucleotide polymorphisms (SNPs) may alter DNA repair capacity ...
