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Article
Open Accessβ2-microglobulin has a different regulatory molecular mechanism between ER+ and ER− breast cancer with HER2−
Previous studies have demonstrated that β2-microglobulin (β2M) promotes the growth and survival of a variety of cancer cells and has different regulatory effects on the expression of Bcl-2 and HER2 in HER2− breas...
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Article
Open AccessAssociation of APEX1 and OGG1 gene polymorphisms with breast cancer risk among Han women in the Gansu Province of China
Genetic variations in key DNA repair genes may influence DNA repair capacity, DNA damage and breast carcinogenesis. The current study aimed to estimate the association of APEX1 and OGG1 polymorphisms with the ris...
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Article
Association analysis of ERCC5 gene polymorphisms with risk of breast cancer in Han women of northwest China
ERCC5 plays an important role in DNA damage repair. Mutations in it will lead to DNA repair defects and genomic instability. Its functional single nucleotide polymorphisms (SNPs) may alter DNA repair capacity ...
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Article
Open AccessCharacterization of β2-microglobulin expression in different types of breast cancer
Βeta-2-microglobulin (β2-M) has been demonstrated as a growth factor and signaling molecule in breast cancer and leukemia. The purpose of the study is to characterize β2-M expression in molecular subtypes of b...
