1,274 Result(s)

Article

Protection against growth of MUC1/sec transfected mammary tumor cells is mediated by an effector cell with perforin-dependent cytotoxicity

T Fu, L Herbert, I Keydar, DM Lopez in Breast Cancer Research (2001)

Article

Childhood acute disseminated encephalomyelitis: the role of brain and spinal cord MRI

Background. It is recognised that the clinical and radiological spectrum of childhood acute disseminated encephalomyelitis (ADEM) is wide. Objective. To determine whether initial MRI features ar...

Pek-Lan Khong, Hok-Kung Ho, Pui-Wai Cheng, Virginia C. Wong… in Pediatric Radiology (2002)

Article

M6P/IGF2Rloss of heterozygosity in head and neck cancer associated with poor patient prognosis

The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) encodes for a multifunctional receptor involved in lysosomal enzyme trafficking, fetal organogenesis, cytotoxic T cell-induced apoptosis a...

Timothy A Jamieson, David M Brizel, J Keith Killian, Yoshihiko Oka… in BMC Cancer (2003)

Article

Correlation of expression of BP1, a homeobox gene, with estrogen receptor status in breast cancer

BP1 is a novel homeobox gene cloned in our laboratory. Our previous studies in leukemia demonstrated that BP1 has oncogenic properties, including as a modulator of cell survival. Here BP1 expression was examin...

Sidney W Fu, Arnold Schwartz, Holly Stevenson, Joseph J Pinzone… in Breast Cancer Research (2003)

Article

Mutagenicity of comfrey (Symphytum Officinale) in rat liver

Comfrey is a rat liver toxin and carcinogen that has been used as a vegetable and herbal remedy by humans. In order to evaluate the mechanisms underlying its carcinogenicity, we examined the mutagenicity of co...

N Mei, L Guo, P P Fu, R H Heflich, T Chen in British Journal of Cancer (2005)

Article

Development of a regional flow cytometry center for diagnosis of childhood leukemia in Central America

S C Howard, D Campana, E Coustan-Smith, F G Antillon, M Bonilla, L Fu, C -H Pui… in Leukemia (2005)

Article

Massive Hematochezia from Acute Hemorrhagic Rectal Ulcer in Patients with Severe Comorbid Illness: Rapid Control of Bleeding by Per Anal Suturing of Bleeder Using Anoretractor

Massive hematochezia from acute hemorrhagic rectal ulcer can arise in patients with severe comorbid illness who are bedridden for long periods. If the bleeder is not found and treated immediately, the bleeding...

Hsin-Yuan Hung M.D., Chung-Rong Changchien M.D.… in Diseases of the Colon & Rectum (2006)

Article

Polymorphisms of XRCC1 genes and risk of nasopharyngeal carcinoma in the Cantonese population

Nasopharyngeal carcinoma (NPC) is one of the most common cancers in southern China. In addition to environmental factors such as Epstein-Barr virus infection and diet, genetic susceptibility has been reported ...

Yun Cao, **ao-** Miao, Ma-Yan Huang, Ling Deng, Li-Fu Hu, Ingemar Ernberg… in BMC Cancer (2006)

Article

Myb proteins inhibit fibroblast transformation by v-Rel

Genes that cause cancer have been divided into two general classes – oncogenes that act in a dominant fashion to transform normal cells into a malignant state, and tumor suppressor genes that act in a dominant...

Shu-ling Fu, Brigitte Ganter, Joseph S Lipsick in Molecular Cancer (2006)

Article

Increased expression of nucleophosmin/B23 in hepatocellular carcinoma and correlation with clinicopathological parameters

Nucleophosmin (NPM, B23, numatrin, NO38) is an abundant nucleolar phosphoprotein involved in multiple cellular functions. Previous evidence indicates that high-level expression of NPM causes uncontrolled cell ...

J-P Yun, J Miao, G G Chen, Q-H Tian, C-Q Zhang, J **ang, J Fu… in British Journal of Cancer (2007)

Article

Primary small cell carcinoma of the esophagus: clinicopathological and immunohistochemical features of 21 cases

Primary small cell carcinoma (SCC) of the esophagus is a rare and aggressive tumor with poor prognosis. In this study, we report the clinicopathological characteristics of 21 cases of small cell carcinoma of t...

**g-** Yun, Mei-Fang Zhang, **-Hui Hou, Qiu-Hong Tian, Jia Fu… in BMC Cancer (2007)

Article

Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells

Stat3 has been classified as a proto-oncogene and constitutive Stat3 signaling appears to be involved in oncogenesis of human cancers. However, whether constitutive Stat3 signaling plays a role in the survival a...

Chun-Liang Chen, Abbey Loy, Ling Cen, Christina Chan, Fu-Chuan Hsieh… in BMC Cancer (2007)

Article

Association of CTLA-4 gene polymorphisms with sporadic breast cancer in Chinese Han population

The host immunogenetic background plays an important role in the development of breast cancer. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is a molecule expressed predominantly on activated T cells and is import...

Lihong Wang, Dalin Li, Zhenkun Fu, Heng Li, Wei Jiang, Dianjun Li in BMC Cancer (2007)

Article

Ductal carcinoma in situ of the breast (DCIS) with heterogeneity of nuclear grade: prognostic effects of quantitative nuclear assessment

Previously, 50% of patients with breast ductal carcinoma in situ (DCIS) had more than one nuclear grade, and neither worst nor predominant nuclear grade was significantly associated with development of invasive c...

Judith-Anne W Chapman, Naomi A Miller, H Lavina A Lickley, ** Qian… in BMC Cancer (2007)

Article

BP1 transcriptionally activates bcl-2and inhibits TNFα-induced cell death in MCF7 breast cancer cells

We have previously shown that the Beta Protein 1 (BP1) homeodomain protein is expressed in 81% of invasive ductal breast carcinomas, and that increased BP1 expression correlates with tumor progression. The pur...

Holly S Stevenson, Sidney W Fu, Joseph J Pinzone, **guen Rheey… in Breast Cancer Research (2007)

Article

Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognosis of invasive breast cancer

Experimental evidence suggests that matrix metalloproteinase-13 (MMP-13) protein may promote breast tumor progression, however, its role is yet to be fully established. Furthermore, it is not clear whether MMP...

Bin Zhang, Xuchen Cao, Yanxue Liu, Wenfeng Cao, Fei Zhang, Shiwu Zhang… in BMC Cancer (2008)

Article

DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein

C-Myc is a short-lived oncoprotein that is destroyed by ubiquitin-mediated proteolysis. Dysregulated accumulation of c-Myc commonly occurs in human cancers. Some of those cases with the dysregulated c-Myc prot...

**g An, Dong-Yan Yang, Qin-Zhi Xu, Shi-Meng Zhang, Yan-Ying Huo… in Molecular Cancer (2008)

Article

Proteomic analysis of differential proteins in pancreatic carcinomas: Effects of MBD1 knock-down by stable RNA interference

Methyl-CpG binding domain protein 1 (MBD1), a suppressor of gene transcription, may be involved in inactivation of tumor suppressor genes during tumorigenesis. Over-expression of MBD1 has been reported in huma...

Chen Liu, Yaohui Chen, **anjun Yu, Chen **, ** Xu, Jiang Long, Quanxing Ni… in BMC Cancer (2008)

Article

Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion

Limited information is available on the effects of progestins on breast cancer progression and metastasis. Cell migration and invasion are central for these processes, and require dynamic cytoskeletal and cell...

**ao-Dong Fu, Maria Silvia Giretti, Lorenzo Goglia, Marina Ines Flamini… in BMC Cancer (2008)

Article

Comparison of molecular phenotypes of ductal carcinoma in situand invasive breast cancer

At least four major categories of invasive breast cancer that are associated with different clinical outcomes have been identified by gene expression profiling: luminal A, luminal B, human epidermal growth fac...

Rulla M Tamimi, Heather J Baer, Jonathan Marotti, Mark Galan… in Breast Cancer Research (2008)