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Open AccessDNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein
C-Myc is a short-lived oncoprotein that is destroyed by ubiquitin-mediated proteolysis. Dysregulated accumulation of c-Myc commonly occurs in human cancers. Some of those cases with the dysregulated c-Myc prot...
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Article
Responsiveness of Smad7 gene to TGF-β1 in the tumorigenesis
Objective: Smad7 was identified as a TGF-β-inducible antagonist of TGF-β signaling and might participate in a negative feedback loop to control TGF-β signaling. In this study, the responsiveness of Smad7 to TG...
