-
Article
Overexpression of cyclin Y in non-small cell lung cancer is associated with cancer cell proliferation
Cyclin Y (CCNY) is a key cell cycle regulator that acts as a growth factor sensor to integrate extracellular signals with the cell cycle machinery. The expression status of CCNY in lung cancer and its clinical...
-
Article
COX-2 silencing inhibits cell proliferation in A549 cell
The aim of this study was to explore the effects on malignant proliferation of A549 cell by silencing cyclooxygenase (COX)-2.
-
Article
Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are Associated with Susceptibility and Chemotherapy Response in Non-small-cell Lung Cancer Patients
Studies of polymorphisms in CYP1A1, CYP2E1, CYP2D6, and GSTM1 and their relationship to lung cancer susceptibility and chemotherapy response have been reported, but the results are not consistent. In this study w...
-
Article
mTOR and PTEN expression in non-small cell lung cancer: analysis by real-time fluorescence quantitative polymerase chain reaction and immunohistochemistry
To detect the expression of mammalian target of rapamycin (mTOR) and PTEN in non-small cell lung cancer (NSCLC), and explore their role in the prognosis of patients with NSCLC.
-
Article
Open AccessDownregulation of Cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9
Cyclophilin A (CypA) is a cytosolic protein possessing peptidyl-prolyl isomerase activity that was recently reported to be overexpressed in several cancers. Here, we explored the biology and molecular mechanis...
-
Article
Open AccessSingle-Cell Electrical Phenoty** Enabling the Classification of Mouse Tumor Samples
Single-cell electrical phenoty** (e.g., specific membrane capacitance (Cm) and cytoplasm conductivity (σp)) has long been regarded as potential label-free biophysical markers in tumor status evaluation. However...
-
Article
Open AccessA Microfabricated 96-Well 3D Assay Enabling High-Throughput Quantification of Cellular Invasion Capabilities
This paper presents a 96-well microfabricated assay to study three-dimensional (3D) invasion of tumor cells. A 3D cluster of tumor cells was first generated within each well by seeding cells onto a micro-patte...
-
Chapter and Conference Paper
Revenue Model for the Inter-City Railway System Based on the Stop Stations and Graded Ticket Fares
With respect to the maximum revenue for the inter-city railway passenger transportation channel system with different grades of parallel trains, this paper has studied the matching relations between the system...
-
Article
Loss of EGFR confers acquired resistance to AZD9291 in an EGFR-mutant non-small cell lung cancer cell line with an epithelial–mesenchymal transition phenotype
AZD9291 is an irreversible, small-molecule inhibitor which has potency against mutant EGFR- and T790M-resistant mutation. Despite the encouraging efficacy in clinical, the acquired resistance will finally occu...
-
Chapter and Conference Paper
Analysis and Prediction of Business and Financial Data Based on LSTM Neural Network
In the context of today’s informatization and big data, the traditional financial management model of power grid projects has fallen behind. The financial department is unable to calculate and control key indi...
-
Article
Open AccessIdentification of potential markers for differentiating epithelial ovarian cancer from ovarian low malignant potential tumors through integrated bioinformatics analysis
Epithelial ovarian cancer (EOC), as a lethal malignancy in women, is often diagnosed as advanced stages. In contrast, intermediating between benign and malignant tumors, ovarian low malignant potential (LMP) t...
-
Article
Open AccessAll-solid anti-resonant single crystal fibers
In this paper, a novel all-solid anti-resonant single crystal fiber (AR-SCF) with high refractive index tubes cladding is proposed. By producing the cladding tubes with high refractive index material, the AR g...
-
Article
Unsupervised learning method for events identification in φ-OTDR
In this paper, an unsupervised-learning method for events-identification in φ-OTDR fiber-optic distributed vibration sensor is proposed. The different vibration-events including blowing, raining, direct and indir...
-
Article
Open AccessNUF2 promotes tumorigenesis by interacting with HNRNPA2B1 via PI3K/AKT/mTOR pathway in ovarian cancer
Ovarian cancer (OC) is one of the commonest and deadliest diseases that threaten the health of women worldwide. It is essential to find out its pathogenic mechanisms and therapeutic targets for OC patients. Al...
-
Article
Open AccessSingle-cell transcriptomics in ovarian cancer identify a metastasis-associated cell cluster overexpressed RAB13
Metastasis, the leading cause of cancer-related death in patients diagnosed with ovarian cancer (OC), is a complex process that involves multiple biological effects. With the continuous development of sequenci...
-
Article
Revenge or forgiveness? The dual-path mechanism of employee co** with experienced incivility from an attribution perspective
Studies on workplace incivility have typically posited that the targets of incivility respond in a “tit-for-tat” manner. Moving beyond this dominant logic, we argue that in some cases, the targets may have a d...
-
Article
Hydrogel derived N, P co-doped 3D honeycomb-like nano porous carbon: CAMN6P-3 and its electrochemical properties
The cost-effective and green preparation of electrocatalysts that are highly effective for both the cathode (reduction of oxygen) and anode (methanal oxidation) reactions is crucial for boosting the developmen...
-
Article
Preparation of Biomass-Based Heteroatom-Doped Porous Carbon and Its Electrochemical Properties
Direct methanol fuel cells (DMFC), as a clean and renewable energy device, can alleviate the problems of energy shortage and environmental pollution. Low-cost and high-performance exploitation of bifunctional ...
-
Article
Challenge or Threat? Examining When and How Employees React Positively and Negatively to Coworkers’ Job Crafting
Previous studies have reported inconsistent or conflicting findings concerning employees’ reactions to coworkers’ job crafting. To reconcile these mixed findings, this study investigates whether, how, and unde...
