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Article
Open AccessNociceptive adenosine A2A receptor on trigeminal nerves orchestrates CGRP release to regulate the progression of oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) associated pain commonly predicts adverse events among patients. This clinical feature indicates the engagement of nociceptors on sensory neurons during the development of m...
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Article
Crystal Structure, Microstructure, and Microwave Dielectric Properties of MgGa2O4 and ZnGa2O4 Ceramics Prepared by a Reaction Sintering Method
The rapidly develo** field of wireless communication technology requires advanced microwave dielectric ceramic materials. Here, spinel-structured MgGa2O4 and ZnGa2O4 ceramics were prepared using a reaction sint...
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Article
Open AccessShaoxia: a web-based interactive analysis platform for single cell RNA sequencing data
In recent years, Single-cell RNA sequencing (scRNA-seq) is increasingly accessible to researchers of many fields. However, interpreting its data demands proficiency in multiple programming languages and bioinf...
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Article
Joint learning of structural and textual information on propagation network by graph attention networks for rumor detection
Due to the advantages in information dissemination, social media is growing rapidly among the public but has also become a medium for the spread of rumors. Given the serious damage rumors bring to society, det...
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Chapter and Conference Paper
Clarification of the Corrosion and Frictional Behavior of Nitrogen-Doped ta-C Coating in Nitride Acid Solution
The ta-C coating, characterized by a high fraction of sp3 hybridized structure, was considered as a potential protective film for preventing bearing steel corrosion in acidic environments due to its chemical iner...
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Article
Mid-Holocene precipitation variations in the Luoyang Basin within the Central Plains of China: a pollen-based reconstruction
In the context of ongoing global warming, understanding the East Asian Summer Monsoon (EASM) dynamics is of great significance for predicting future climate changes. This study reconstructed the mid-Holocene p...
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Article
Multiple myeloma initially manifesting as a solitary deep ulcer on the tongue: a case study and literature review
Multiple myeloma (MM) is a malignant disease associated with clonal plasma cell proliferative disorder, characterized by extensive infiltration of clonal plasma cells in the bone marrow, for which a proportion...
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Article
Open AccessEffect of acupuncture for patients with knee osteoarthritis: study protocol for a double-dummy randomized controlled trial
Acupuncture has been used to relieve chronic pain in patients with knee osteoarthritis (KOA), but the evidence is contradictory. Therefore, we carefully designed a double-dummy randomized controlled trial (RCT...
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Article
Impeded Lüders banding during forward and reverse phase transformations in a cold-rolled NiTi shape memory alloy
Real time, in situ, synchrotron X-ray diffraction and digital imaging correlation are applied to investigate the forward and reverse phase transformations in a cold-rolled shape memory alloy
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Article
Open AccessSurgical treatment of Shone’s syndrome and patent ductus arteriosus in an adult
Shone’s syndrome is a rare complex congenital anomaly. The classical definition consists of four anomalies: supravalvular mitral membrane, parachute mitral valve (PMV), subaortic stenosis, and coarctation of t...
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Article
Task Offloading of Intelligent Building Based on CO–HHO Algorithm in Edge Computing
With the rapid development of intelligent devices, the intelligence of buildings is becoming more and more obvious, which leads to the rapid growth of data generated by building users. The existing network ban...
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Article
Co-amorphous Drug Delivery Systems: a Review of Physical Stability, In Vitro and In Vivo Performance
Over the past few decades, co-amorphous solids have been used as a promising approach for delivering poorly water-soluble drugs. Co-amorphous solids, comprising pharmacologically relevant drug substances or ex...
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Article
Open AccessEfficacy of manual acupuncture, electro-acupuncture, and warm acupuncture for knee osteoarthritis: study protocol for a randomized controlled trial
Acupuncture is one of the most popular complementary and alternative treatments for knee osteoarthritis (KOA). There are many methods of acupuncture in the treatment of KOA, and the effects are different. Acco...
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Article
Open AccessObservation of curative effect on meridian theory-based extracorporeal shock wave therapy for non-specific low back pain: study protocol for a randomized controlled trial
Non-specific low back pain (NLBP) is a major global socioeconomic burden, and the prevalence of NLBP is still on the rise. At present, there is no ideal drug to cure this disease. This may be the reason why pa...
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Chapter and Conference Paper
Analysis and Numerical Simulation of Semi-circle Bending Fatigue Crack Propagation of Asphalt Mixture
In order to study the fatigue crack propagation characteristics of asphalt mixture, a model of fatigue crack dynamically propagating was established based on the Paris law modified with fracture energy release...
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Article
Open AccessEGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1
The Hippo pathway is frequently dysregulated in cancer, leading to the unrestrained activity of its downstream targets, YAP/TAZ, and aberrant tumor growth. However, the precise mechanisms leading to YAP/TAZ ac...
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Article
Holocene vegetation and hydrology variations and their associations with climate changes: a multi-proxy analysis of a sediment core from an alpine basin in the middle Tianshan Mountains
We in this paper present a multi-proxy study of a 186-cm-long lacustrine sediment core (i.e., BY Core) obtained from the Youerdusi Basin in the middle Tianshan Mountains in an attempt to disentangle the causal...
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Chapter and Conference Paper
Optimal Control and Reinforcement Learning for Robot: A Survey
Along with the development of systems and their applications, conventional control approaches are limited by system complexity and functions. The development of reinforcement learning and optimal control has b...
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Article
Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK–YAP signaling axis
Prostate cancer (PCa) innervation contributes to the progression of PCa. However, the precise impact of innervation on PCa cells is still poorly understood. By focusing on muscarinic receptors, which are activ...
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Article
Simulation of a Silicon Heterojunction Solar Cell with a Gradient Do** Emitter Layer
A silicon heterojunction solar cell structure consisting of a gradient do** emitter layer, which possesses a potential to obtain high power conversion efficiency, is explored by the numerical simulation tool...