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  1. No Access

    Article

    Screening of Strain from Reconstituted Sheet Tobacco Making High-Yield Enzyme and Aroma

    Reconstituted sheet tobacco (RST) is critical to the quality of cigarette. The purpose of this study was to extract and cultivate bacteria from tobacco leaf stalks, scraps, and concentrate from RST production ...

    Chun-Xue Yang, Deng Zhang, Hui Ma in Proceedings of the National Academy of Sci… (2024)

  2. Article

    Open Access

    Validation of continuous intraabdominal pressure measurement: feasibility and accuracy assessment using a capsular device in in-vivo studies

    Monitoring Intraabdominal Pressure (IAP) is essential in critical care, as elevated IAP can lead to severe complications, including Abdominal Compartment Syndrome (ACS). Advances in technology, such as digital...

    Dong-Ru Ho, Chi-Tung Cheng, Chun-Hsiang Ouyang in World Journal of Emergency Surgery (2024)

  3. Article

    Open Access

    Influence of vaccination on critical COVID-19 patients with acute respiratory failure: a retrospective cohort study

    Despite vaccines’ effectiveness in reducing COVID-19 infection rates and disease severity, their impact on critical patients presenting with acute respiratory failure is elusive. The aim of this study was to f...

    Hsiao-Chin Shen, Jhong-Ru Huang, Chuan-Yen Sun in European Journal of Medical Research (2024)

  4. Article

    Open Access

    Comparison of efficacy and safety of equivalent doses of remimazolam versus propofol for gastroscopy anesthesia in elderly patients

    Remimazolam, a novel intravenous anesthetic, has been proven to be safe and efficacious in the gastroscopy setting among the elderly. However, reports comparing the effectiveness and safety of using equivalent...

    Di Chen, Min Liao, **ao-ru Wu, Tang-yuan-meng Zhao, Hu Sun in Scientific Reports (2024)

  5. Article

    Open Access

    Microbes translocation from oral cavity to nasopharyngeal carcinoma in patients

    The presence of oral microbes in extra-oral sites is linked to gastrointestinal cancers. However, their potential ectopically colonization in the nasopharynx and impact on local cancer development remains unce...

    Ying Liao, Yan-**a Wu, Minzhong Tang, Yi-Wei Chen, **-Ru **e in Nature Communications (2024)

  6. No Access

    Article

    Molecularly imprinted dispersive micro solid-phase extraction and tandem derivatization for the determination of histamine in fermented wines

    Histamine causes allergic reactions and can serve as an indicator for assessing food quality. This study designed and developed a dispersive micro solid-phase extraction (D-μSPE) method that combined the advan...

    Fang-Yi Liao, **g-Ru Weng, Ying-Chi Lin in Analytical and Bioanalytical Chemistry (2024)

  7. Article

    Open Access

    Clinical characteristics and outcomes among critically ill patients with cancer and COVID-19-related acute respiratory failure

    Coronavirus disease 2019 (COVID-19) has affected individuals worldwide, and patients with cancer are particularly vulnerable to COVID-19-related severe illness, respiratory failure, and mortality. The relation...

    Ying-Ting Liao, Hsiao-Chin Shen, Jhong-Ru Huang, Chuan-Yen Sun in BMC Pulmonary Medicine (2024)

  8. Article

    Open Access

    Myasthenia gravis and independent risk factors for recurrent infection: a retrospective cohort study

    Approximately 10% to 20% of myasthenia gravis (MG) patients have experienced a myasthenic crisis (MC), which contributes to morbidity and mortality. MC triggered by infection is associated with poor outcomes. ...

    Chia-Yin Chien, Chun-Wei Chang, Ming-Feng Liao, Chun-Che Chu, Long-Sun Ro in BMC Neurology (2023)

  9. No Access

    Article

    A Cre knockin mouse reveals specific expression of Agouti gene in mesenchymal lineage cells in multiple organs and provides a unique tool for conditional gene targeting

    The mouse Agouti gene encodes a paracrine signaling factor which promotes melanocytes to produce yellow instead of black pigment. It has been reported that Agouti mRNA is confined to the dermal papilla after birt...

    **ng-Ru Shen, He-Li Zhang, Xu-Bo Zhao, Yang-Ge Wang, **ao-Yang Tan in Transgenic Research (2023)

  10. Article

    Open Access

    Early relapse is an adverse prognostic factor for survival outcomes in patients with oral cavity squamous cell carcinoma: results from a nationwide registry study

    The prognostic significance of the relapse interval in patients with resected oral cavity squamous cell carcinoma (OCSCC) is a matter of ongoing debate. In this large-scale, registry-based, nationwide study, w...

    Chi-Ying Tsai, Yu-Wen Wen, Shu-Ru Lee, Shu-Hang Ng, Chung-Jan Kang, Li-Yu Lee in BMC Cancer (2023)

  11. Article

    Open Access

    PINK1/Parkin-mediated mitophagy inhibits osteoblast apoptosis induced by advanced oxidation protein products

    Osteoblast apoptosis plays an important role in age-related bone loss and osteoporosis. Our previous study revealed that advanced oxidation protein products (AOPPs) could induce nicotinamide adenine dinucleoti...

    Wei Li, Wang-Sheng Jiang, Ya-Ru Su, Ke-Wu Tu, Lin Zou in Cell Death & Disease (2023)

  12. Article

    Open Access

    A radiomics-based deep learning approach to predict progression free-survival after tyrosine kinase inhibitor therapy in non-small cell lung cancer

    The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are a first-line therapy for non-small cell lung cancer (NSCLC) with EGFR mutations. Approximately half of the patients with EGFR-muta...

    Chia-Feng Lu, Chien-Yi Liao, Heng-Sheng Chao, Hwa-Yen Chiu, Ting-Wei Wang in Cancer Imaging (2023)

  13. No Access

    Chapter and Conference Paper

    Development of a Path-to-Follow Nozzle for Ultraviolet-Assisted Three-Dimensional Bioprinting Technology

    Ultraviolet-assisted three-dimensional bioprinting (UV-3DP) combines tissue engineering and extruding-based additive manufacturing. Photocrosslinking is performed by irradiating a specific area with UV light. ...

    Chao-Yaug Liao, Fang-Ru Shen, Shan-hui Hsu in Advances in Mechanism and Machine Science (2023)

  14. Article

    Open Access

    OrchidBase 5.0: updates of the orchid genome knowledgebase

    Containing the largest number of species, the orchid family provides not only materials for studying plant evolution and environmental adaptation, but economically and culturally important ornamental plants fo...

    You-Yi Chen, Chung‐I Li, Yu-Yun Hsiao, Sau-Yee Ho, Zhe-Bin Zhang in BMC Plant Biology (2022)

  15. No Access

    Article

    Intraoperative hemodynamic stability in peripheral nerve block patients undergoing diabetic foot surgery

    Yun-Ru Lu, Shang-Ru Yeoh, Chun-Kai Jen, Kuan-Wen Chen in Clinical Autonomic Research (2022)

  16. Article

    Improving transitional care through online communication skills training

    As the aging population is increasing significantly, the communication skills training (CST) on transitional care (TC) is insufficient.

    Ji-Tseng Fang, Shih-Ying Chen, Lan-Yen Yang in Aging Clinical and Experimental Research (2022)

  17. No Access

    Article

    Impact of comorbidities on the prognosis of pediatric vasovagal syncope

    Ya-Ru Wang, Xue-Ying Li, Jun-Bao Du, Yan Sun, Wen-Rui Xu in World Journal of Pediatrics (2022)

  18. Article

    Open Access

    Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use

    K1 capsular polysaccharide (CPS)-associated Klebsiella pneumoniae is the primary cause of pyogenic liver abscesses (PLA) in Asia. Patients with PLA often have serious complications, ultimately leading to a mortal...

    I-Fan Tu, Tzu-Lung Lin, Feng-Ling Yang, I-Ming Lee in Journal of Biomedical Science (2022)

  19. No Access

    Article

    P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib

    Mantle cell lymphoma (MCL) is a lymphoproliferative disorder lacking reliable therapies. PI3K pathway contributes to the pathogenesis of MCL, serving as a potential target. However, idelalisib, an FDA-approved...

    **ao-ru Zhou, **ao Li, Li-** Liao, Jie Han, **g Huang in Acta Pharmacologica Sinica (2022)

  20. No Access

    Article

    Clinical Outcomes of Taiwanese Patients with Resected Oral Cavity Squamous Cell Carcinoma Who Underwent Reconstruction with Free Versus Local Flaps

    We sought to compare the clinical outcomes of Taiwanese patients with resected oral cavity squamous cell carcinoma (OCSCC) who underwent reconstruction with free versus local flaps.

    Chun-Ta Liao MD, Yu-Wen Wen PhD, Shu-Ru Lee PhD in Annals of Surgical Oncology (2022)

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