149 Result(s)

Article

Chromatin-binding in vivo of the erythroid kruppel-like factor, EKLF, in the murine globin loci

EKLF is an erythroid-specific, zinc finger-containing transcription factor essential for the activation of the mammalian beta globin gene in erythroid cells of definitive lineage. We have prepared a polyclonal...

Yu-Chiau Shyu, Shau-Ching Wen, Tung-Liang Lee, **n Chen, Chia-Tse Hsu… in Cell Research (2006)

Article

Expression changes of hippocampal energy metabolism enzymes contribute to behavioural abnormalities during chronic morphine treatment

Dependence and impairment of learning and memory are two well-established features caused by abused drugs such as opioids. The hippocampus is an important region associated with both drug dependence and learni...

**ao-Lan Chen, Gang Lu, Ying-**a Gong, Liang-Cai Zhao, Jie Chen… in Cell Research (2007)

Article

Altered expression patterns of lipid metabolism genes in an animal model of HCV core-related, nonobese, modest hepatic steatosis

Because the gene expression patterns of nonobese hepatic steatosis in affected patients remain unclear, we sought to explore these patterns using an animal model of nonobese hepatic steatosis.

Ming-Ling Chang, Chau-Ting Yeh, Jeng-Chang Chen, Chau-Chun Huang… in BMC Genomics (2008)

Article

Emodin targets the β-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization

The natural product Emodin demonstrates a wide range of pharmacological properties including anticancer, anti-inflammatory, antiproliferation, vasorelaxant and anti-H. pylori activities. Although its H. pylori in...

**g Chen, Liang Zhang, Yu Zhang, Haitao Zhang, Jiamu Du, Jian** Ding… in BMC Microbiology (2009)

Article

SnoRNAs from the filamentous fungus Neurospora crassa: structural, functional and evolutionary insights

SnoRNAs represent an excellent model for studying the structural and functional evolution of small non-coding RNAs involved in the post-transcriptional modification machinery for rRNAs and snRNAs in eukaryotic...

Na Liu, Zhen-Dong **ao, Chun-Hong Yu, Peng Shao, Yin-Tong Liang… in BMC Genomics (2009)

Article

De novo assembly and characterization of the root transcriptome of Aegilops variabilis during an interaction with the cereal cyst nematode

Aegilops variabilis No.1 is highly resistant to cereal cyst nematode (CCN). However, a lack of genomic information has restricted studies on CCN resistance genes in Ae. variabilis and has limited genetic applicat...

De-Lin Xu, Hai Long, Jun-Jun Liang, Jie Zhang, **n Chen, **g-Liang Li… in BMC Genomics (2012)

Article

Development of simple sequence repeat (SSR) markers from a genome survey of Chinese bayberry (Myrica rubra)

Chinese bayberry (Myrica rubra Sieb. and Zucc.) is a subtropical evergreen tree originating in China. It has been cultivated in southern China for several thousand years, and annual production has reached 1.1 mil...

Yun Jiao, Hui-min Jia, **ong-wei Li, Ming-liang Chai, Hui-juan Jia… in BMC Genomics (2012)

Article

Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation

Su Chen, Juan Li, Da-Liang Wang, Fang-Lin Sun in Cell Research (2012)

Article

Global transcriptome profiles of Camellia sinensis during cold acclimation

Tea is the most popular non-alcoholic health beverage in the world. The tea plant (Camellia sinensis (L.) O. Kuntze) needs to undergo a cold acclimation process to enhance its freezing tolerance in winter. Change...

**n-Chao Wang, Qiong-Yi Zhao, Chun-Lei Ma, Zong-Hong Zhang, Hong-Li Cao… in BMC Genomics (2013)

Article

Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene

Trans-splicing, a process involving the cleavage and joining of two separate transcripts, can expand the transcriptome and proteome in eukaryotes. Chimeric RNAs generated by trans-splicing are increasingly des...

Guang-**g Hu, Jia Chen, **ao-Nan Zhao, Jia-Jia Xu, Dong-Qing Guo, Ming Lu… in Cell Research (2013)

Article

Peach genetic resources: diversity, population structure and linkage disequilibrium

Peach (Prunus persica (L.) Batsch) is one of the most important model fruits in the Rosaceae family. Native to the west of China, where peach has been domesticated for more than 4,000 years, its cultivation sprea...

**ong-wei Li, **an-qiao Meng, Hui-juan Jia, Ming-liang Yu, Rui-juan Ma… in BMC Genetics (2013)

Article

Piperlongumine induces autophagy by targeting p38 signaling

Piperlongumine (PL), a natural product isolated from the plant species Piper longum L., can selectively induce apoptotic cell death in cancer cells by targeting the stress response to reactive oxygen species (...

Y Wang, J-W Wang, X **ao, Y Shan, B Xue, G Jiang, Q He, J Chen… in Cell Death & Disease (2013)

Article

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

The methyltransferase like 3 (METTL3)-containing methyltransferase complex catalyzes the N6-methyladenosine (m6A) formation, a novel epitranscriptomic marker; however, the nature of this complex remains largel...

**ao-Li **, Bao-Fa Sun, Lu Wang, Wen **ao, **n Yang, Wen-Jia Wang… in Cell Research (2014)

Article

Exploration of microRNAs in porcine milk exosomes

Breast milk contains complex nutrients and facilitates the maturation of various biological systems in infants. Exosomes, membranous vesicles of endocytic origin found in different body fluids such as milk, ca...

Ting Chen, Qian-Yun **, Rui-Song Ye, **ao Cheng, Qi-En Qi, Song-Bo Wang… in BMC Genomics (2014)

Article

A stress-induced cellular aging model with postnatal neural stem cells

Aging refers to the physical and functional decline of the tissues over time that often leads to age-related degenerative diseases. Accumulating evidence implicates that the senescence of neural stem cells (NS...

C-M Dong, X-L Wang, G-M Wang, W-J Zhang, L Zhu, S Gao, D-J Yang… in Cell Death & Disease (2014)

Article

The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes

The tyrosine phosphorylation barcode encoded in C-terminus of HER2 and its ubiquitination regulate diverse HER2 functions. PTPN18 was reported as a HER2 phosphatase; however, the exact mechanism by which it de...

Hong-Mei Wang, Yun-Fei Xu, Shang-Lei Ning, Du-**ao Yang, Yi Li, Yu-Jie Du… in Cell Research (2014)

Article

Transcriptome analysis of the effect of Vibrio alginolyticus infection on the innate immunity-related complement pathway in Epinephelus coioides

Orange-spotted grouper (Epinephelus coioides) with protogynous hermaphroditic features are one of the most economically important aquaculture species in Taiwan. However, larvae stage grouper are susceptible to in...

Yi-Da Wang, Shin-Jie Huang, Hong-Nong Chou, Wen-Liang Liao, Hong-Yi Gong… in BMC Genomics (2014)