36 Result(s)
within
Immunology
Microbiology
**ang-Hui **e
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Article
Molecular cloning and characterization of a cytosolic heat shock protein 70 from Naegleria fowleri
A gene encoding a cytosolic heat shock protein 70 from pathogenic Naegleria fowleri (Nf-cHSP70) was identified. The Nf-cHSP70 was 2,062 bp in length with an open reading frame of 1,980 bp encoding 659 amino acid ...
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Article
Heat shock protein 70 of Naegleria fowleri is important factor for proliferation and in vitro cytotoxicity
To evaluate the role of heat shock 70 protein (HSP70) in free-living amoeba, a constitutive and inducible heat shock 70 gene of pathogenic Naegleria fowleri has previously been cloned, characterized, and named as...
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Article
Evaluating the evolution of G. lamblia based on the small nucleolar RNAs identified from Archaea and unicellular eukaryotes
The evolutionary position of Giardia lamblia has been challenged in recent years. Comparison of the snoRNAs identified from Archaea and unicellular eukaryotes shows that G. lamblia snoRNAs are more similar in mos...
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Article
Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum
Artemether and artesunate, derivatives of the antimalarial artemisinin, as well as their main metabolite, dihydroartemisinin, all exhibit antischistosomal activities. The purpose of the current study was to co...
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Effect of the in vivo activity of dihydroartemisinin against Schistosoma mansoni infection in mice
Dihydroartemisinin, formerly known as an antimalarial drug, is the main metabolite of the mother compound artemisinins, as well as of artemether and artesunate. It has been shown that the drug exhibits antisch...
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Article
Effects of aqueous extract of Capsicum frutescens (Solanaceae) against the fish ectoparasite Ichthyophthirius multifiliis
Ichthyophthirius multifiliis is an important fish ectoparasite that often results in significant economic losses to freshwater aquaculture. The search of alternative substances to control infecti...
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Comparative profiling of microRNAs in male and female adults of Ascaris suum
Ascaris nematodes, which cause ascariasis in humans and pigs, are among the most important nematodes from both health and economic perspectives. microRNA (miRNA) is now recognized as key regulato...
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Article
The mRNA level of the galectin-10 of Angiostrongylus cantonensis induced by reactive oxygen stress
Galectin plays an important role in host–parasite interactions. In this study, we identified a novel gene encoding galectin-10 (AcGal-10) from the cDNA library of Angiostrongylus cantonensis and characterized its...
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Article
Open AccessFoot-and-mouth disease virus-like particles produced by a SUMO fusion protein system in Escherichia coli induce potent protective immune responses in guinea pigs, swine and cattle
Foot-and-mouth disease virus (FMDV) causes a highly contagious infection in cloven-hoofed animals. The format of FMD virus-like particles (VLP) as a non-replicating particulate vaccine candidate is a promising...
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Article
Open AccessThe shrimp IKK–NF-κB signaling pathway regulates antimicrobial peptide expression and may be subverted by white spot syndrome virus to facilitate viral gene expression
The IκB kinases IKKα and IKKβ and the IKK-related kinases TANK-binding kinase 1 (TBK1) and IKKε are the master regulators of the NF-κB signaling pathway. Although this pathway has been extensively studied in m...
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Article
A B-1a cell subset induces Foxp3− T cells with regulatory activity through an IL-10-independent pathway
Regulatory T (Treg) cells play a critical role in the maintenance of tolerance. B-1a cells belong to a specific and functionally important B-cell subset that exerts its regulatory role through the production o...
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Article
Prevalence and molecular characterization of Cryptosporidium spp. in dairy cattle, northwest China
Cryptosporidium spp. cause enteric diseases in a wide range of animals, including dairy cattle. However, limited information is available regarding prevalence and molecular characterization of Cr...
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Rapid detection and identification of four major Schistosoma species by high-resolution melt (HRM) analysis
Schistosomiasis, caused by blood flukes belonging to several species of the genus Schistosoma, is a serious and widespread parasitic disease. Accurate and rapid differentiation of these etiological agents of anim...
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Transcriptomic analysis of global changes in cytokine expression in mouse spleens following acute Toxoplasma gondii infection
Toxoplasma gondii is a global pathogen that infects a wide range of animals and humans. During T. gondii infection, the spleen plays an important role in coordinating the adaptive and inn...
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Article
Recombinase polymerase amplification (RPA) combined with lateral flow (LF) strip for equipment-free detection of Cryptosporidium spp. oocysts in dairy cattle feces
Cryptosporidium is a widespread protozoan parasite that infects a large number of vertebrate animals, resulting in varying degrees of diarrhea or even death. As dairy cattle feces is an i...
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Article
Occurrence and distribution of yellow grub trematodes (Clinostomum complanatum) infection in Taiwan
Digenetic trematodes of the genus Clinostomum are widely distributed in many species of freshwater fish and are known to cause the zoonotic disease Halzoun. Humans may become accidental hosts if they ingest raw f...
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Article
Characterization of the complete mitochondrial genome of Marshallagia marshalli and phylogenetic implications for the superfamily Trichostrongyloidea
Marshallagia marshalli (Nematoda: Trichostrongylidae) infection can lead to serious parasitic gastroenteritis in sheep, goat, and wild ruminant, causing significant socioeconomic losses worldwide...
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Article
Open AccessGlobal discovery of small RNAs in the fish pathogen Edwardsiella piscicida: key regulator of adversity and pathogenicity
Recently, bacterial small RNA (sRNA) has been shown to be involved as a key regulator in stress responses. sRNAs of Edwardsiella piscicida, an important aquatic pathogen, are not well characterized to date. In th...
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Article
Effect of regulatory T cells on the efficacy of the fatty acid-binding protein vaccine against Schistosoma japonicum
Schistosomiasis is one of the most devastating parasitic diseases, making it imperative to develop efficient vaccines to control the causative flatworms called schistosomes. Regulatory T cells (Tregs) and the ...
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Article
Helminths protect against type 1 diabetes: effects and mechanisms
Type 1 diabetes (T1D) is an autoimmune disease in which cells of the immune system destroy pancreatic β cells, which secrete insulin. The high prevalence of T1D in developed societies may be explained by envir...
