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Open AccessMuscle texture features on preoperative MRI for diagnosis and assessment of severity of congenital muscular torticollis
To develop an objective method based on texture analysis on MRI for diagnosis of congenital muscular torticollis (CMT).
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Open AccessClinical analysis of 1301 children with hand and foot fractures and growth plate injuries
Fractures of hands and feet are common in children, but relevant epidemiological studies are currently lacking. We aim to study the epidemiological characteristics of hand and foot fractures and growth plate i...
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Article
Open AccessPLMSearch: Protein language model powers accurate and fast sequence search for remote homology
Homologous protein search is one of the most commonly used methods for protein annotation and analysis. Compared to structure search, detecting distant evolutionary relationships from sequences alone remains c...
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Open AccessDifferentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations
The underrepresentation of human genomic resources from Southern Chinese populations limited their health equality in the precision medicine era and complete understanding of their genetic formation, admixture...
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Open AccessTask-state skin potential abnormalities can distinguish major depressive disorder and bipolar depression from healthy controls
Early detection of bipolar depression (BPD) and major depressive disorder (MDD) has been challenging due to the lack of reliable and easily measurable biological markers. This study aimed to investigate the ac...
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Open AccessCorrelation study on firing temperature and color of plain pottery excavated from the Tang Dynasty tomb of Liu **g in Shaanxi, China
Plain pottery excavated from the Tang Dynasty tomb of Liu **g was taken as the research object. The color, chemical composition, microstructure, and phase were tested to investigate the influencing factors of...
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Article
Open AccessEffective binning of metagenomic contigs using contrastive multi-view representation learning
Contig binning plays a crucial role in metagenomic data analysis by grou** contigs from the same or closely related genomes. However, existing binning methods face challenges in practical applications due to...
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Open AccessNuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1
Cytoskeleton is extensively recruited by flaviviruses for their infection. In this study, we uncovered an essential role of a nuclear membrane protein, SAD1/UNC84 domain protein 2 (SUN2) linking cytoskeleton a...
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Open AccessCorrelation analysis and gender differences of cognitive function based on mini-mental state examination (MMSE) and suicidal tendency in patients with schizophrenia
The aim of this study was to investigate the correlation and gender differences between cognition and suicidal tendency in patients with schizophrenia.
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Open AccessAltered levels of cytokine, T- and B-lymphocytes, and PD-1 expression rates in drug-naïve schizophrenia patients with acute phase
Many studies have investigated the changes of immune cells and proinflammatory cytokines in patients with acute schizophrenia, but few studies have investigated the functional phenotypes of immune cells and th...
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Open AccessCorrection: Acute exposure to gold nanoparticles aggravates lipopolysaccharide-induced liver injury by amplifying apoptosis via ROS-mediated macrophage-hepatocyte crosstalk
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Open AccessChanges in abundant and rare microbial taxa that dominated the formation of soil carbon pool during short-term dryland-to-paddy conversion
Land consolidation of dryland-to-paddy conversion (LC-DtPC) has rapidly changed the farmland ecological environment in the short term, thereby affecting the microbial community and its mediated soil carbon seq...
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Publisher Correction: Crop switching can enhance environmental sustainability and farmer incomes in China
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Open AccessPrevalence and clinical correlates of abnormal lipid metabolism in first-episode and drug-naïve patients with major depressive disorder with abnormal glucose metabolism
Comorbid glucose metabolism abnormalities are very common in patients with major depressive disorder (MDD), and glucose metabolism and lipid metabolism are closely related. However, there are few researches on...
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Article
Crop switching can enhance environmental sustainability and farmer incomes in China
Achieving food-system sustainability is a multidimensional challenge. In China, a doubling of crop production since 1990 has compromised other dimensions of sustainability1,2. Although the country is promoting va...
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Open AccessEfficacy of a Deep Learning System for Screening Myopic Maculopathy Based on Color Fundus Photographs
The maculopathy in highly myopic eyes is complex. Its clinical diagnosis is a huge workload and subjective. To simply and quickly classify pathologic myopia (PM), a deep learning algorithm was developed and as...
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Article
Open AccessIntegrated metabolome and transcriptome analysis unveils novel pathway involved in the fruit coloration of Nitraria tangutorum Bobr.
The desert shrub Nitraria tangutorum Bobr. is important for its resistance to salt and alkali in Northwest China. It is an ecologically important species in this region and provides edible and medicinal berries. ...
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Open AccessMetaBinner: a high-performance and stand-alone ensemble binning method to recover individual genomes from complex microbial communities
Binning aims to recover microbial genomes from metagenomic data. For complex metagenomic communities, the available binning methods are far from satisfactory, which usually do not fully use different types of ...
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Open AccessSelection and validation of appropriate reference genes for RT–qPCR analysis of Nitraria sibirica under various abiotic stresses
Nitraria sibirica Pall. is a halophytic shrub with strong environmental adaptability that can survive in extremely saline-alkali and drought-impacted environments. Gene expression analysis aids in the exploration...
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Open AccessEfficacy and Safety of Consecutive Use of 1% and 0.01% Atropine for Myopia Control in Chinese Children: The Atropine for Children and Adolescent Myopia Progression Study
The purpose of this study was to investigate the efficacy and safety of consecutive use of 1% and 0.01% atropine compared with 0.01% atropine alone over 1 year.