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Article
Hydroxychavicol, a polyphenol from Piper betle leaf extract, induces cell cycle arrest and apoptosis in TP53-resistant HT-29 colon cancer cells
This study aims to elucidate the antiproliferative mechanism of hydroxychavicol (HC). Its effects on cell cycle, apoptosis, and the expression of c-Jun N-terminal kinase (JNK) and P38 mitogen-activated protein...
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Article
Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death
Extracellular senile plaques and intracellular neurofibrillary tangles are the neuropathological findings of the Alzheimer’s disease (AD). Based on the amyloid cascade hypothesis, the main component of senile ...
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Article
Anti-adipogenic effects of extracts of Ficus deltoidea var. deltoidea and var. angustifolia on 3T3-L1 adipocytes
Objective: This study examined the anti-adipogenic effects of extracts of Ficus deltoidea var. deltoidia and var. angustifolia, a natural slimming aid, on 3T3-L1 adipocytes. Methods: Methanol and water extracts o...
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Article
Morphological and biochemical responses of Oryza sativa L. (cultivar MR219) to ion beam irradiation
Heavy ion beam, which has emerged as a new mutagen in the mutation breeding of crops and ornamental plants, is expected to result in the induction of novel mutations. This study investigates the morphological ...
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Article
Comparative effects of plant growth regulators on leaf and stem explants of Labisia pumila var. alata
Labisia pumila var. alata, commonly known as ‘Kacip Fatimah’ or ‘Selusuh Fatimah’ in Southeast Asia, is traditionally used by members of the Malay community because of its post-partum ...