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    Article

    Hydroxychavicol, a polyphenol from Piper betle leaf extract, induces cell cycle arrest and apoptosis in TP53-resistant HT-29 colon cancer cells

    This study aims to elucidate the antiproliferative mechanism of hydroxychavicol (HC). Its effects on cell cycle, apoptosis, and the expression of c-Jun N-terminal kinase (JNK) and P38 mitogen-activated protein...

    Aiysvariyah Rajedadram, Kar Yong Pin in Journal of Zhejiang University-SCIENCE B (2021)

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    Article

    Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death

    Extracellular senile plaques and intracellular neurofibrillary tangles are the neuropathological findings of the Alzheimer’s disease (AD). Based on the amyloid cascade hypothesis, the main component of senile ...

    Yong Qi Leong, Khuen Yen Ng, Soi Moi Chye, Anna Pick Kiong Ling in Metabolic Brain Disease (2020)

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    Anti-adipogenic effects of extracts of Ficus deltoidea var. deltoidea and var. angustifolia on 3T3-L1 adipocytes

    Objective: This study examined the anti-adipogenic effects of extracts of Ficus deltoidea var. deltoidia and var. angustifolia, a natural slimming aid, on 3T3-L1 adipocytes. Methods: Methanol and water extracts o...

    Shiau Mei Woon, Yew Wei Seng in Journal of Zhejiang University SCIENCE B (2014)

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    Morphological and biochemical responses of Oryza sativa L. (cultivar MR219) to ion beam irradiation

    Heavy ion beam, which has emerged as a new mutagen in the mutation breeding of crops and ornamental plants, is expected to result in the induction of novel mutations. This study investigates the morphological ...

    Anna Pick Kiong Ling, Ying Chian Ung in Journal of Zhejiang University SCIENCE B (2013)

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    Article

    Comparative effects of plant growth regulators on leaf and stem explants of Labisia pumila var. alata

    Labisia pumila var. alata, commonly known as ‘Kacip Fatimah’ or ‘Selusuh Fatimah’ in Southeast Asia, is traditionally used by members of the Malay community because of its post-partum ...

    Anna Pick Kiong Ling, Kinn Poay Tan in Journal of Zhejiang University SCIENCE B (2013)