6,713 Result(s)
within
**-hui Chen
-
Article
Phosphodiesterase 8 (PDE8): Distribution and Cellular Expression and Association with Alzheimer’s Disease
Phosphodiesterase 8 (PDE8), as a member of PDE superfamily, specifically promotes the hydrolysis and degradation of intracellular cyclic adenosine monophosphate (cAMP), which may be associated with pathogenesi...
-
Article
An improved and efficient coercion-resistant measure for electronic voting system
The integrity of electronic voting systems is critical in safeguarding the democratic process worldwide. This study addresses the twin challenges of bribery and coercion that undermine most existing electronic...
-
Article
Brain-Targeting Emodin Mitigates Ischemic Stroke via Inhibiting AQP4-Mediated Swelling and Neuroinflammation
Failure to achieve target-specific delivery to ischemic brain sites has hampered the clinical efficacy of newly developed therapies for ischemic stroke. Emodin, an active ingredient isolated from traditional C...
-
Article
Exploring the potential of combining transcranial magnetic stimulation and electroencephalography to investigate mild cognitive impairment and Alzheimer’s disease: a systematic review
Transcranial magnetic stimulation (TMS) and electroencephalography (EEG) are non-invasive techniques used for neuromodulation and recording brain electrical activity, respectively. The integration of TMS-EEG h...
-
Article
Study on Acoustic Emission and Crack Propagation Characteristics of Single-Fissured Sandstone with Different Angles Under Uniaxial Compression
The uniaxial compression tests are conducted on single-fissured sandstone with different angles, and the effect of fissure angle (β) on mechanical properties, acoustic emission (AE) features, crack propagation ch...
-
Article
The association between cardiac T2*BOLD and quantitative flow ratio (QFR) in the diagnosis of stenotic coronary arteries in patients with multi-vessel coronary artery disease
T2*BOLD is based on myocardial deoxyhemoglobin content to reflect the state of myocardial oxygenation. Quantitative flow ratio is a tool for assessing coronary blood flow based on invasive coronary angiography.
-
Article
Open AccessIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and treatment. This study explored ONECUT2’s role and the specific mechanism...
-
Article
Open AccessHarnessing virus flexibility to selectively capture and profile rare circulating target cells for precise cancer subty**
The effective isolation of rare target cells, such as circulating tumor cells, from whole blood is still challenging due to the lack of a capturing surface with strong target-binding affinity and non-target-ce...
-
Article
Open AccessSurvival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study
Most gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has significantly improved the survival of patients with GISTs. We aimed to evalu...
-
Article
Clinical characteristics of membranous nephropathy after allogeneic hematopoietic stem cell transplantation: A real-world multicenter study
Membranous nephropathy (MN) is a rare complication that can occur after allogeneic hematopoietic stem cell transplantation (allo-HSCT). MN patients may develop nephrotic syndrome or even kidney failure, which ...
-
Article
Risk Factors and Predictive Nomogram for Survival in Elderly Patients with Brain Glioma
To determine the factors that contribute to the survival of elderly individuals diagnosed with brain glioma and develop a prognostic nomogram.
-
Article
Programming an efficient technique for designing smart C-doped MIC with dual self-protection for information and high-energy
Constructing self-protected metastable intermolecular composites (MICs) enables the regulation of microstructures towards boosting controllable detonation performance, and also prevents information leakage, wh...
-
Article
Open AccessA generalized uniform placement of alters on spherical surface (U-PASS) for visualizing general weighted networks
Network visualization is an important tool for extracting information from the structure and configuration of a network, especially when the network includes weighted edges and nodes with attribute information...
-
Article
Open AccessCorrelation between serum trimethylamine-N-oxide and body fat distribution in middle-aged and older adults: a prospective cohort study
Trimethylamine-N-oxide (TMAO) is linked with obesity, while limited evidence on its relationship with body fat distribution. Herein, we investigated the associations between serum TMAO and longitudinal change ...
-
Article
Open AccessA-to-I RNA co-editing predicts clinical outcomes and is associated with immune cells infiltration in hepatocellular carcinoma
Aberrant RNA editing has emerged as a pivotal factor in the pathogenesis of hepatocellular carcinoma (HCC), but the impact of RNA co-editing within HCC remains underexplored. We used a multi-step algorithm to ...
-
Article
Combining satellite data and artificial intelligence with a crop growth model to enhance rice yield estimation and crop management practices
Rice is the staple food of more than half of the world’s population, especially in Asia, where rice provides more than 50% of the caloric supply for at least 520 million people, most of them are either extreme...
-
Article
Open AccessATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8+ T cells
Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress anti-tumor immunity remain unclear. Here, we show th...
-
Article
Open AccessCultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
The Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the number of Atribacterota genome sequences retrieved from environmental samples ...
-
Article
Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
-
Article
Analysis of Phenotypes Associated with Deficiency of PAX6 Haplotypes in Chinese Aniridia Families
To examine the clinical phenotype and genetic deficiencies present in Chinese aniridia families with PAX6 haplotype deficiency.
