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  1. No Access

    Article

    ImmunoPET/CT imaging of clear cell renal cell carcinoma with [18F]RCCB6: a first-in-human study

    The cluster of differentiation (CD70) is a potential biomarker of clear cell renal cell carcinoma (ccRCC). This study aims to develop CD70-targeted immuno-positron emission tomography/computed tomography (immu...

    Qianyun Wu, Yanfei Wu, You Zhang, Yihui Guan… in European Journal of Nuclear Medicine and M… (2024)

  2. No Access

    Article

    ImmunoPET imaging of Trop2 expression in solid tumors with nanobody tracers

    The high expression of the transmembrane glycoprotein trophoblast cell-surface antigen 2 (Trop2) was strongly associated with the progression of solid tumors, including pancreatic and gastric cancers. Our stud...

    Wei Huang, Chenyi Liang, You Zhang, Di Zhang… in European Journal of Nuclear Medicine and M… (2024)

  3. No Access

    Article

    GPC3-targeted immunoPET imaging of hepatocellular carcinomas

    Early detection of hepatocellular carcinoma (HCC) remains a clinical challenge. Glypican 3 (GPC3) is a proteoglycan highly specific for HCC and is a potential diagnostic and therapeutic target for HCC. This wo...

    Shuxian An, Di Zhang, You Zhang, Cheng Wang… in European Journal of Nuclear Medicine and M… (2022)

  4. No Access

    Article

    ImmunoPET imaging of multiple myeloma with [68Ga]Ga-NOTA-Nb1053

    Multiple myeloma (MM) remains incurable and its diagnosis relies heavily on bone marrow aspiration and biopsy. CD38 is a glycoprotein highly specific for MM. Antibody therapeutics (e.g., daratumumab) targeting...

    Cheng Wang, Yumei Chen, Yun Nan Hou… in European Journal of Nuclear Medicine and M… (2021)