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Progressive multifocal leukoencephalopathy and spectrum of predisposing conditions: a 20-year retrospective cohort study in a tertiary center in São Paulo, Brazil
BackgroundEpidemiological studies on predisposing conditions and outcomes of progressive multifocal leukoencephalopathy (PML) cases have been carried...
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A Translational Approach to Using Endocannabinoid Modulators for Targeting Opioid-Associated Memory
Purpose of ReviewIt is well established that learning and memory are central to substance dependence. Convincing basic and clinical documents...
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Critical Care of Spinal Cord Injury
Purpose of ReviewSpinal cord injury (SCI) is a major cause of morbidity and mortality, posing a significant financial burden on patients and the...
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Clinical features and underlying etiology of children with Lennox–Gastaut syndrome
ObjectiveLennox–Gastaut Syndrome (LGS) is characterized by the presence of multiple seizure types and encompasses a heterogenous group of etiologies....
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Circular walking is useful for assessing the risk of falls in early progressive supranuclear palsy
BackgroundProgressive supranuclear palsy (PSP) is characterized by early onset postural instability and frequent falls. Circular walking necessitates...
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COPD, PRISm and lung function reduction affect the brain cortical structure: a Mendelian randomization study
Chronic obstructive pulmonary disease (COPD) has been associated with alterations in the brain cortical structure. Nonetheless, the causality between...
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Digital outcome measures are associated with brain atrophy in patients with multiple sclerosis
BackgroundDigital monitoring of people with multiple sclerosis (PwMS) using smartphone-based monitoring tools is a promising method to assess disease...
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Therapeutic potential of transient receptor potential (TRP) channels in psychiatric disorders
Psychiatric disorders such as Bipolar disorder, Anxiety, Major depressive disorder, Schizophrenia, Attention-deficit/hyperactivity disorder, as well...
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The effect of plate location on radial nerve palsy recovery time associated with humeral shaft fractures
BackgroundThis study aims to investigate the influence of plate placement on nerve regeneration in humerus fractures accompanied by radial nerve...
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Perioperative management of Takotsubo cardiomyopathy: an overview
Resembling the morphology of Japanese polyp vessels, the classic form of Takotsubo cardiomyopathy is characterized by the presence of systolic...
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Correlation between surgical position and neck pain in patients undergoing thyroidectomy: a prospective observational study
BackgroundThyroid diseases are one of the most common health problems worldwide. Although they represent a necessary step in order to perform...
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Aktuelle Herausforderungen in der Behandlung der Opioidabhängigkeit
BackgroundThe number of persons using opioids has increased worldwide in the last decade, particularly the use of opioid analgesics in North America...
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Absolute values of regional ventilation-perfusion mismatch in patients with ARDS monitored by electrical impedance tomography and the role of dead space and shunt compensation
BackgroundAssessment of regional ventilation/perfusion (V′/Q) mismatch using electrical impedance tomography (EIT) represents a promising advancement...
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Investigation into the role of H2-Ab1 in vascular remodeling in pulmonary arterial hypertension via Bioinformatics
BackgroundPulmonary arterial hypertension (PAH) is a progressive disease of vascular remodeling characterized by persistent pulmonary arterial...
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High blood glucose variability may predict poor outcomes in patients with spontaneous cerebellar hemorrhage undergoing surgical operation: a retrospective study
BackgroundElevated blood glucose (BG) variability has been reported as an independent risk factor for poor prognosis in a variety of diseases. This...
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Rheumatoid meningitis in the absence of rheumatoid arthritis: 2 cases
Rheumatoid meningitis (RM) is a rare extra-articular manifestation of rheumatoid arthritis (RA) that has been increasingly recognized by...
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Treatment with robot-assisted gait trainer Walkbot along with physiotherapy vs. isolated physiotherapy in children and adolescents with cerebral palsy. Experimental study
BackgroundImproving walking ability is a key objective in the treatment of children and adolescents with cerebral palsy, since it directly affects...
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Evaluation of the effect of trendelenburg position duration on intracranial pressure in laparoscopic hysterectomies using ultrasonographic optic nerve sheath diameter measurements
BackgroundDuring laparoscopic surgery, pneumoperitoneum and Trendelenburg positioning applied to provide better surgical vision can cause many...
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Integrated clustering of multiple immune marker trajectories reveals different immunotypes in severely injured patients
BackgroundThe immune response of critically ill patients, such as those with sepsis, severe trauma, or major surgery, is heterogeneous and dynamic,...
