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Chapter and Conference Paper
Flow Cytometric Analysis of Intracellular Myeloperoxidase and Lactoferrin in Leukemia Diagnosis
The immunological characterization of leukemic blast cells in terms of their lineage commitment and differentiation stage has so far mainly been based on the analysis of surface marker molecules. Mainly for te...
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Chapter and Conference Paper
Myeloid-Associated Antigen Expression in Childhood Acute Lymphoblastic Leukemia
Coexpression of myeloid-associated antigens has been demonstrated in several studies on acute lymphoblastic leukemia (ALL). The proportion of cases with this aberrant antigen expression (myA+ ALL) ranged from 5% ...
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Chapter and Conference Paper
Immunological Phenoty** of Blood and Bone Marrow Cells From Patients with Myelodysplastic Syndromes
Since the discovery of the hybridoma technique monoclonal antibodies (MoAb) have been widely used in various fields of medicine [1], and immunological phenty** using MoAbs has become a routine technology for...
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Chapter and Conference Paper
Association of GP40/CD7+ Acute Myeloblastic Leukemia and Chromosome 5 Aberrations
Immunological investigation of human leukemias revealed conservation of lineage specificity in the majority of cases. However, deviations of maturation-linked phenotype (i.e., asynchronous differentiation comp...
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Chapter and Conference Paper
Behandlung von steroidresistenten Abstoßungsreaktionen nach Transplantation solider Organe mit einem monoklonalen Anti-CD 4 Antikörper
Nach Transplantation solider Organe sind Abstoßungsreaktionen trotz verbes serter prophylaktischer Immunsuppression immer noch eine bedeutsame und häufige Komplikation. Insbesonders jene Abstoßungen, bei denen...
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Chapter and Conference Paper
Diagnostic Value of Monoclonal Antibodies to Leucocyte — Differentiation Antigens in Lymphoid and Nonlymphoid Leukemias
Monoclonal antibodies, by definition, are specific for a given antigenic determinant. When directed against a cell-type-specific antigenic determinant, such antibodies can be used for cell-type recognition. T...
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Chapter and Conference Paper
Leucocyte Malignancies
A series of six monoclonal antibodies reactive with hematopoietic differentiation antigens expressed at different stages of myelocytic and erythrocytic differentiation have been developed. One of these antibod...
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Chapter and Conference Paper
Chronic Lymphatic Leukemia Cells Bear IgM Receptors
It is now generally accepted that the majority of chronic lymphatic leukemias (CLL) are malignant B cell proliferations. These leukemic B cells differ however in several respects from normal B cells; they freq...
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Chapter and Conference Paper
Lymphocyte Subpopulations in Lymphatic Tissues and Blood of Patients with Malignant Lymphomas
The distribution of lymphocyte subpopulations in mononuclear cell suspensions isolated from the peripheral blood and from various lymphatic tissues of patients with different malignant lymphomas was determined...