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Chapter
Diagnosis of Echinococciasis: Parasitological, Immunological, and Molecular Tools
Echinococcosis is a serious zoonotic disease caused by the larvae of several Echinococcus species forming a hydatid cyst, which can parasitize humans and animals. Diagnosis is a prerequisite for disease preventio...
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Chapter
Exotoxins of Staphylococcus aureus
Staphylococcus aureus produces a variety of exotoxins, which are important virulence factors for S. aureus-related diseases. Representatively, staphylococcal enterotoxins induce staphylococcal food-born poisoning...
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Chapter
Animal Models of Tuberculosis
Tuberculosis (TB) is an important zoonotic disease caused by infection with Mycobacterium tuberculosis (Mtb) complex and has a significant impact on public health. Animal models are suitable tools to mimic the cl...
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Chapter
Scabies and Secondary Infections
Scabies infection may be complicated by secondary bacterial infections, most commonly due to Staphylococcus aureus and group A Streptococcus. Direct trauma from scratching and specific proteins secreted by the sc...
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Chapter
Biopharmaceutical Potential of Ophiocordyceps sinensis for Human Health
Ophiocordyceps sinensis is an entomopathogenic fungus used in traditional Chinese and Tibetan medicine for over 2000 years. It is also commonly consumed in Asia for nutritional purposes. To authenticate the vario...
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Chapter
Advances in the Genetic Manipulation of Nosema bombycis
The microsporidium Nosema bombycis can infect and transmit both vertically and horizontally in multiple lepidopteran insects including silkworms and crop pests. While there have been several studies on the N. bom...
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Chapter
Inflammatory Components of the Thyroid Cancer Microenvironment: An Avenue for Identification of Novel Biomarkers
The incidence of thyroid cancer in the United States is on the rise with an appreciably high disease recurrence rate of 20–30%. Anaplastic thyroid cancer (ATC), although rare in occurrence, is an aggressive fo...
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Chapter
Disruption of Cell-Cell Communication in Anaplastic Thyroid Cancer as an Immunotherapeutic Opportunity
Thyroid cancer incidence is increasing at an alarming rate, almost tripling every decade. About 44,280 new cases of thyroid cancer (12,150 in men and 32,130 in women) are estimated to be diagnosed in 2021, wit...
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Chapter
Basic Biology of Oral Microbes
The cell is the fundamental unit of all living organisms. Various subunit structures and chemical substances found on and inside the cell make complex cellular functions possible. Understanding the morphology ...
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Chapter
The Oral Microbiome Bank of China
The Human Microbiome Project (HMP) promoted further understanding of human oral microbes. However, research on the human oral microbiota has not made as much progress as research on the gut microbiota. Current...
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Chapter
Gut Microbiota and Endocrine Disorder
The gut microbiome contains trillions of commensal microorganisms that maintain a symbiotic relationship with the host, and its profound effects on gastrointestinal diseases have been widely described. Recentl...
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Chapter
Invasion of Oral Microbiota into the Gut
The oral microbiota is associated with oral diseases and digestive systemic diseases. Nevertheless, the causal relationship between them has not been completely elucidated, and colonization of the gut by oral ...
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Chapter
Supragingival Microbes
This chapter mainly introduces the common microbes in supragingival plaque. Supragingival plaque refers to the plaque above the gingival margin of the tooth neck, including groove plaque, smooth surface plaque...
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Chapter
Oral Mucosal Microbes
This chapter mainly covers the microbes that cause mucosal infection. Many microorganisms can invade the oral mucosa, causing infectious stomatitis. Infectious stomatitis is classified as primary and secondary...
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Chapter
New Oral Microbial Isolations
More than 700 different species of bacteria, viruses, fungi, mycoplasma, and chlamydia live in the human oral cavity, collectively known as the oral microbiome. The ecological imbalance of oral microbiome can ...
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Chapter
Discovery of Cell-Surface Vimentin (CSV) as a Sarcoma Target and Development of CSV-Targeted IL12 Immune Therapy
This chapter discusses a novel target of osteosarcoma (OS), cell-surface vimentin (CSV), and a novel generation of interleukin-12 (IL12), CSV-targeted IL12, for treating OS tumor metastasis. Vimentin is a know...
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Chapter
Mycobiome Dysbiosis in Oral Lichen Planus
The biodiversity of the mycobiome, an important component of the oral microbial community, and the roles of fungal-bacterial and fungal-immune system interactions in the pathogenesis of oral lichen planus (OLP...
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Chapter
Galectins in Host Defense Against Microbial Infections
Galectins are differentially expressed in a variety of cell types, including immune cells, and characterized by the affinity for β-galactoside–containing glycans. There are fifteen galectin members in mammals....
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Chapter
Techniques for Oral Microbiology
In recent years, with the rapid development of molecular biology, microecology, systems biology, and other disciplines, oral microbiology has been transformed from the traditional microbiology which is based o...
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Chapter
Subgingival Microbes
This chapter mainly introduces the common microbes in subgingival plaque. Subgingival plaque refers to the plaque located below the gingival margin and distributed in the gingival groove or periodontal pocket....