1,425 Result(s)
within
Chapter
Qi** Li
Biomedicine
English
-
Chapter
Biosensing Technologies for Detection of Extracellular Vesicles
Extracellular vesicles (EVs) are novel biomarkers evaluated during liquid biopsy and are involved in many physiological functions in cells as well as various pathological processes in diseases. There is an urg...
-
Chapter
Extracellular Vesicle Biomarkers for Immune Disorders
Abnormalities in the immune system can cause a range of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, and scleroderma. Extracellular vesicles (EVs) play regulatory roles in t...
-
Chapter
Extracellular Vesicle Biomarkers for Renal Diseases
Extracellular vesicles (EVs) are emerging as a new mechanism of intercellular communication in renal disease. EVs originating from the renal system can be readily detected in urine and may therefore represent ...
-
Chapter
Monoclonal Antibodies: From Structure to Therapeutic Application
The exciting field of therapeutic monoclonal antibodies (mAbs) had its origins when Köhler and Milstein presented their murine hybridoma technology in 1975 (Kohler, Milstein. Nature. 256(5517):495–497, 1975). ...
-
Chapter
The Mechanisms of Interaction Between Extracellular Vesicles and Target Cells
The ability of extracellular vesicles (EVs) to transmit signals on the cell surface and/or transfer their contents from donor to recipient cells to elicit phenotypic changes has been shown to be highly relevan...
-
Chapter
Genetic Databases and Online Ring Chromosome Registry
The rapid adaptations of genomic technologies into genetic testing require knowledge-based genetic databases and disease registries in various capacities. General Web resources for clinical and diagnostic gene...
-
Chapter
Screening and Clinical Verification of Extracellular Vesicle Biomarkers
Extracellular vesicles (EVs), lipid bilayer-encapsulated membrane particles carrying proteins, lipids, nucleic acids, and sugars, are shed by most cells into the extracellular milieu and function to mediate in...
-
Chapter
Ring Chromosome 16
Ring chromosome 16 (RC16) is an ultra-rare chromosomal structural abnormality with only eight cases reported in the literature. Included in this case series are those eight published cases, plus our unpublishe...
-
Chapter
Diagnosis of Echinococciasis: Parasitological, Immunological, and Molecular Tools
Echinococcosis is a serious zoonotic disease caused by the larvae of several Echinococcus species forming a hydatid cyst, which can parasitize humans and animals. Diagnosis is a prerequisite for disease preventio...
-
Chapter
Ring Chromosome 9
Ring chromosome 9 (RC9) is a rare structural chromosome abnormality. Karyoty**, fluorescence in situ hybridization (FISH), chromosome microarray analysis (CMA), and genomic sequencing have been used to defin...
-
Chapter
Extracellular Vesicle Biomarkers for Thrombosis
Extracellular vesicles (EVs) participate in thrombosis via the functions of molecule expression on their surfaces, including tissue factor (TF) and phosphatidylserine (PS). TF is an important protein involved ...
-
Chapter
Historical Perspective of Human Ring Chromosomes
Human ring chromosomes (RCs) are a rare type of chromosomal structural abnormality. Current cytogenomic analysis revealed heterogeneous genomic rearrangements in the ring structures, variable levels of dynamic...
-
Chapter
Etiology of HFMD
Hand, foot, and mouth disease (HFMD) is caused by multiple viruses in the genus Enterovirus, which include the well-known polioviruses (PVs), coxsackieviruses A and B (CV-A and CV-B), and enteric cytopathic hu...
-
Chapter
The Expression of Non B Cell-Derived Immunoglobulins
Although V(D)J recombination and immunoglobulin (Ig) production are traditionally recognised to occur only in B lymphocytes and plasma cells, the expression of Igs in non-lymphoid cells, which we call non B ce...
-
Chapter
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Targeted Therapeutics for Cystic Fibrosis
Treatment of the common life-limiting genetic disease cystic fibrosis (CF) has been transformed by small molecule therapeutics that target the root cause of the disease, pathogenic variants in the ATP-binding ...
-
Chapter
Astrocytes: The Rising Stars that Regulate Synaptic Plasticity and Long-Term Memory Formation
For decades, our understanding of the mechanisms underlying long-term synaptic plasticity and memory is largely limited to the roles played by neuronal elements. Astrocytes, the most abundant glia cells in the...
-
Chapter
Stem Cell-Derived Extracellular Vesicles (EVs) for Disease Therapy
Stem cell therapy has become one of the most advanced technologies in the field of regenerative medicine and has attracted considerable attention worldwide. Recent studies have revealed that stem cells exert t...
-
Chapter
Exotoxins of Staphylococcus aureus
Staphylococcus aureus produces a variety of exotoxins, which are important virulence factors for S. aureus-related diseases. Representatively, staphylococcal enterotoxins induce staphylococcal food-born poisoning...
-
Chapter
Emerging Nanotechnology for the Treatment and Diagnosis of Parkinson’s Disease (PD) and Alzheimer’s Disease (AD)
Introduction: and are neurodegenerative diseases distinguished by the aggregation of pathologic proteins leading to the respective onset of motor dysfunction and cognitive decline, particularly in memory. Eme...
-
Chapter
The Significance of Biomaterials in Stem Cell-Based Regenerative Medicine
Introduction: Stem cell-based therapeutic strategies have shown tremendous potential in attenuating tissue damage and facilitating tissue repair and . The therapeutic benefits of are largely dependent on the e...
