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Chapter
Immune Evasive Stem Cell Islets
Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of insulin-secreting β cells by the immune system (American Diabetes, A., Diabetes Care 32 Suppl 1:S62–67, 2009). It is characterized by...
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Chapter
Bioengineered Vascularized Insulin Producing Endocrine Tissues
Islet transplantation is a promising treatment for type 1 diabetes (T1D), but limited islet engraftment hampers its success. In vivo, islets require time to remodel the hepatic parenchyma and establish their o...
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Chapter
Minimally Invasive Pancreatectomy plus Islet Autotransplantation for Benign Tumors of the Pancreatic Neck and Body
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Chapter
Modulation of Early Inflammatory Reactions to Promote Engraftment and Function of Transplanted Pancreatic Islets in Autoimmune Diabetes
We acknowledge that successful long-term islet survival in the liver and immune tolerance to intrahepatic islet antigens are highly dependent upon the initial inflammatory and priming events that occur at this...
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Chapter and Conference Paper
Gluten-Free Diet in Subjects at Risk for Type 1 Diabetes: A Tool for Delaying Progression to Clinical Disease?