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Chapter
Recent Update on Pyridoxine Derivatives as Anticancer Agents with Overview on Its Patents
Water-soluble vitamin B6 is made up of six molecules consisting of pyridoxine, pyridoxal, and its phosphorylated derivatives, each of which has a pyridine ring in its centre. Various epidemiological, in vivo, ...
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Chapter
Mitigation of Dementia and Alzheimer’s Disease with Lipophilic Vitamins and Their Derivatives: Preclinical and Clinical Evidence
Recent research has been exploring the link between vitamin deficiencies and the pathogenesis of neurodegenerative ailments such as cognition impairment, dementia, and Alzheimer’s disease (AD). Lipophilic vita...
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Chapter
Unraveling the Mechanisms of Hydrophilic Vitamins in Alzheimer’s and Parkinson’s: Preclinical and Clinical Evidence
(AD) (PD) are characterized by neuronal loss and cognitive and physical decline. The precise origins of remain unknown but oxidative damage, impaired proteosis are believed to be causal elements in dise...
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Chapter
Quercetin: A Promising Flavonoid for the Therapy of Cardiac Hypertrophy and Heart Failure Mediated by the Renin Angiotensin System
(RAS) plays an essential role in regulating levels in the body and maintaining cardiovascular homeostasis. However, overactivation of RAS leads to and cardiac overload, especially in the , causing . As ...
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Chapter
Anticancer Role of Natural Phenolic Acids by Targeting Angiotensin-Converting Enzyme (ACE)
Recently, it has become obvious that renin-angiotensin system (RAS) plays an important role in cancer progression through angiotensin converting enzyme (ACE), involving activation and upregulation of multiple ...
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Chapter
Role of Renin Angiotensin System in the Pathophysiology of Coronary Heart Disease: Advancements in Diagnosis, Therapy and Preventive Strategies
The incidence of (CHD) has been escalating over the years, and epidemiological data suggests that CHD causes nearly 17.9 million deaths worldwide annually. Myocardial infarction and stroke resulting from CHD...
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Chapter
Therapeutic Interventions of Endocannabinoid Signaling in Obesity-Related Cardiovascular Dysfunction
is a major risk factor involved in the progression . The aggravation is primarily linked to the release of pro-inflammatory cytokines. The endocannabinoid system (ECS) plays an important role in various di...
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Chapter
Role of Flavonoids in Obesity Induced Cardiovascular Dysfunction
Obesity is found to be a contributing risk factor for Cardiovascular Dysfunction (CVD), disease (CHD) is found to be linked to the release of several proinflammatory mediators. The fluctuation in the lev...
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Chapter
Pathophysiology of Obesity-Related Non-communicable Chronic Diseases and Advancements in Preventive Strategies
is characterized by an excessive accumulation of (WAT) causing increases in and (BMI >30 kg/m2). WAT stores energy and releases free fatty acids, but it is also a dynamic that triggers the production o...
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Chapter
Absorption, Metabolism, and Disposition of Flavonoids and Their Role in the Prevention of Distinctive Cancer Types
Flavonoids consist of a large family of polyphenolic molecules like flavones, flavonols, flavanols, isoflavones, flavanones, and anthocyanidins which are ubiquitously distributed in nature and are present in a...
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Chapter
Potentials of Phytopharmaceuticals for Treating Microbiological and Oxidative Stress-Induced Type 2 Diabetes
Currently, type 2 diabetes is one of the most widespread noncommunicable maladies that inflict more than 400 million people globally. Diabetes-induced oxidative stress and distortion in gastrointestinal microb...
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Chapter
Nutraceutical Approaches in the Management of Cardiovascular Dysfunctions Associated with Diabetes Mellitus
Diabetes is a prime risk factor in cardiovascular disease (CVD), which includes peripheral vascular disease, coronary artery disease, and cerebrovascular disease. Management of cardiovascular dysfunctions asso...