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    Chapter

    Evolutionary Dynamics of a Population of Cells with a Toxin Suppressor Gene

    Environmental changes are known to trigger evolutionary changes, e.g. by favoring higher mutation rates. We study the evolutionary dynamics of a delayed stochastic genetic circuit using a simulator developed f...

    Antti Häkkinen, Fred G. Biddle in Transactions on Computational Systems Biol… (2011)

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    Chapter

    Biological Limits of Hand Preference Learning Hiding Behind the Genes

    Biological limits of learning are the cto our understanding of learning and memory. We are conducting a detailed investigation of structure and function of gene regulatory networks in a biological system of le...

    Fred G. Biddle, Brenda A. Eales in Information Processing and Biological Systems (2011)

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    Chapter

    Genetic Variability of Purine Nucleoside Phosphorylase in the Mouse

    The inherited human deficiency of purine nucleoside phosphorylase is associated primarily with cellular immune dysfunction1. We have begun to screen for quantitative activity variants of purine nucleoside phospho...

    Floyd F. Snyder, Fred G. Biddle, Trevor Lukey in Purine Metabolism in Man-IV (1984)