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Chapter
Regulation of Motor Behavior by Dopamine Receptor Subtypes
The neurotransmitter dopamine mediates various behavioral functions in the central nervous system (CNS). The major dopamine pathway involved in motor function is the nigrostriatal pathway, which originates fro...
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Chapter
Electrophysiological Consequences of D2 and/or D3 Receptor Knockout by Antisense Oligonucleotides in Nigrostriatal Dopaminergic Neurons
Mesencephalic dopaminergic neurons possess receptors for their own neurotransmitter, dopamine, at both somatodendritic as well as axon terminal regions. These receptors are termed autoreceptors and act to modu...
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Chapter
Neuropharmacological Effects of (−)-Stepholidine and its Analogues on Brain Dopaminergic System
Tetrahydroprotoberberines (THPBs), a series of natural products isolated from the Chinese herbs Corydalis and Stephania, have been proven to be novel dopamine (DA) receptor antagonists, among them, (-)-stephol...