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    Chapter

    Adjuvant Therapies in Renal Cell Carcinoma

    Renal cell carcinoma is a heterogenous disease with differential outcomes among different patients’ populations. While a large portion of patients with localized renal cell carcinoma are cured with surgical ne...

    Elizabeth Pan, Justine Panian in Integrating Multidisciplinary Treatment fo… (2023)

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    Chapter

    Diet Modulates Gut Microbiome and Metabolites in Non-alcoholic Fatty Liver Diseases

    Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease globally. NAFLD is a spectrum disease ranging from simple steatosis, non-alcoholic steatohepatitis (NASH), fibrosis/cirrhos...

    Yasi Pan, **ang Zhang in Microbiome in Gastrointestinal Cancer (2023)

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    Instruments and Reagents for Biochemical Analysis

    Biochemical diagnosis is often used for the testing of basic items such as liver function, kidney function, blood glucose, and blood lipid. By measuring the content (activity) of specific biochemical substance...

    Zuojun Zou, Yanshang Ma, Dalei Li, Nengke Pan in In Vitro Diagnostic Industry in China (2023)

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    Digestive Tract Disease

    Stomach, one of the body’s digestive system, is the expanding part of esophagus. The shape of the stomach can be affected by the state of fullness. When the stomach is completely empty, it is slightly tubular ...

    Genyan Liu, Yuqiao Xu, Shiyang Pan, Weijuan Song in Clinical Molecular Diagnostics (2021)

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    DNA Methylation Detection Techniques

    Gene expression can be mediated by DNA methylation, modifications of histones, and positioning of nucleosome along the DNA in which DNA methylation is intensely studied. There are many methods designed to be a...

    Shiyang Pan, Jiexin Zhang in Clinical Molecular Diagnostics (2021)

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    Chapter

    Molecules in Body Systems

    All biological systems are composed of the same types of chemical molecules and employ similar principles of organization at the cellular level [1].

    Shiyang Pan, **ncen Duan in Clinical Molecular Diagnostics (2021)

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    Lung Disease

    The lungs are the respiratory organs and the important hematopoietic organs of the human body. Lungs are located in the chest on both sides of the heart

    Liang Ming, Ting Sun, Haitao Ding, Juan He, Wenjuan Wu in Clinical Molecular Diagnostics (2021)

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    Molecules in Signal Pathways

    Cell signal transduction is essential for human life. Signal transduction pathways participate in all cell life activities, such as cell metabolism, cell division, cell differentiation, cell functional activit...

    Shiyang Pan, Wei Zhang in Clinical Molecular Diagnostics (2021)

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    Histiocytic and Dendritic Cell Neoplasms

    Histiocytic and dendritic cell neoplasms are rare and represent a heterogeneous group of mature histiocytic and dendritic cell proliferations with unique clinicopathologic characteristics. Recurrent molecular ...

    Nathan Paulson, ** Wang, Zenggang Pan in Practical Oncologic Molecular Pathology (2021)

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    Chapter

    Translation Research of Novel Biomarker

    A biomarker has been defined as “an indicator that can be objectively measured and evaluated of a physiological as well as a pathological processes or pharmacologic responses to a therapeutic intervention.” Mi...

    Shiyang Pan, Yuexinzi ** in Clinical Molecular Diagnostics (2021)

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    Chapter

    Molecular Testing in Ovarian Cancer: Recommendations and Treatment Considerations

    Ovarian cancer is a heterogeneous disease that encompasses a number of different histologic subtypes, including high-grade serous carcinomas (the most frequent), endometrioid, and clear cell, mucinous, and low...

    Kathy Pan, Mihaela C. Cristea in Oncology in the Precision Medicine Era (2020)

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    Chapter

    Supportive Medical Management of Brain Metastases Patients Including Treatment Complications

    Brain metastases are the most common intracranial neoplasms and are associated with an array of clinical problems that require complex medical management. These include focal neurologic deficits, seizures, cog...

    Peter C. Pan, Laura E. Donovan, Rajiv S. Magge in Radiotherapy in Managing Brain Metastases (2020)

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    Chapter

    B-Cells in Cancer Immunology: For or Against Cancer Growth?

    The role played by B-cells in cancer immunology is complex and somewhat controversial. Depending upon their state of activation, B-cells have had divergent roles in T-cell differentiation and effector function...

    Qiao Li, Qin Pan, Huimin Tao, **ao-Lian Zhang, Shiang Huang in Cancer Immunology (2020)

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    Chapter

    Cytotoxic Chemotherapy and Targeted Therapy in Nasopharyngeal Cancer

    Over the past several decades, there has been a notable decrease in the incidence and mortality of nasopharyngeal carcinoma. Lifestyle modification, improvements in screening and diagnosis, and advances in rad...

    Jonathan Pan, Jennifer Johnson in Critical Issues in Head and Neck Oncology (2018)

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    Next-Generation Ultrasonic Theranostic Agents for Molecular Imaging and Therapy: Design, Preparation, and Biomedical Application

    Ultrasound contrast agents (UCAs) such as microbubbles can oscillate and vibrate when a sonic energy field is applied, making them several thousand times more reflective than normal body tissues and emitting s...

    Hairong Zheng, Yuanyi Zheng, Fei Yan, Mian Chen, Pan Li in Advances in Nanotheranostics II (2016)

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    Chapter

    Hereditary Kidney Cancer Syndromes

    In 2014, there are over 65,000 newly diagnosed cases of kidney cancer, responsible for nearly 14,000 deaths. While the death rates fell by 0.9 % per year from 2006 to 2010, it is still very much a lethal disea...

    Shu Pan MD, Brian Shuch MD in Kidney Cancer (2015)

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    Chapter

    Immunologic Approaches to Targeting Cancer Stem Cells

    Cancer stem cells represent a small subset of tumor cells which have the ability to self-renew and generate the diverse cells that comprise tumors. They are responsible for local tumor recurrence and distant m...

    Qin Pan PhD, Qiao Li PhD, Ning Ning MD, Yingxin Xu MD in Cancer Immunology (2015)

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    Chapter

    B Cells in Cancer Immunology: For or Against Cancer Growth?

    The role played by B cells in cancer immunology is complex and somewhat controversial. Depending upon their state of activation, B cells have had divergent roles in T cell differentiation and effector function...

    Qiao Li PhD, Qin Pan PhD, Huimin Tao MSc, **ao-Lian Zhang PhD in Cancer Immunology (2015)

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    Chapter

    Molecular Imaging in Urology

    Imaging plays an integral role in urology by providing anatomical detail and diagnostic insight of urologic diseases. Cross-sectional imaging technologies including computed tomography (CT), magnetic resonance...

    Ying Pan PhD, Mark Hsu MD, Joseph C. Liao MD in Advances in Image-Guided Urologic Surgery (2015)

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    Chapter

    Stomach, Small and Large Intestines

  21. Abdominopelvic radiation therapy plays an important role in the curative and palliative treatment for a large proportion of tumors arising from the abdomin...

  22. Stephen L. Harris, Charlie C. Pan in ALERT • Adverse Late Effects of Cancer Tre… (2014)

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