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Article
Open AccessEfficacy of Wearable low-intensity pulsed Ultrasound treatment in the Movement disorder in Parkinson’s disease (the SWUMP trial): protocol for a single-site, double-blind, randomized controlled trial
Parkinson’s disease (PD) is a progressive, neurodegenerative illness marked by the loss of dopaminergic neurons, causing motor symptoms. Oral levodopa replacement therapy remains the gold standard in the treat...
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Article
Open AccessPromoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS scavenging
Impaired collateral formation is a major factor contributing to poor prognosis in type 2 diabetes mellitus (T2DM) patients with atherosclerotic cardiovascular disease. However, the current pharmacological trea...
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Article
Open AccessEngineering a triple-functional magnetic gel driving mutually-synergistic mild hyperthermia-starvation therapy for osteosarcoma treatment and augmented bone regeneration
Malignant bone tumors result in high rates of disability and death and are difficult to treat in terms of killing tumors and repairing bone defects. Compared with other hyperthermia strategies, magnetic hypert...
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Article
Open AccessEfficacy of low-intensity pulsed ultrasound for the treatment of viral pneumonia: study protocol for a randomized controlled trial
Viral pneumonia has always been a problem faced by clinicians because of its insidious onset, strong infectivity, and lack of effective drugs. Patients with advanced age or underlying diseases may experience m...
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Chapter and Conference Paper
Fine-Grained Hand Bone Segmentation via Adaptive Multi-dimensional Convolutional Network and Anatomy-Constraint Loss
Ultrasound imaging is a promising tool for clinical hand examination due to its radiation-free and cost-effective nature. To mitigate the impact of ultrasonic imaging defects on accurate clinical diagnosis, au...
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Article
Open AccessCorrection: Biodegradable reduce expenditure bioreactor for augmented sonodynamic therapy via regulating tumor hypoxia and inducing pro‑death autophagy
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Article
Open AccessFailure mode effect and criticality analysis of ultrasound device by classification tracking
Medical ultrasound device has been more and more widely used in the hospital and Its safety risk is significantly increased when failures occur. However, there is a lack of quantitative risk assessments of dif...
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Article
Open AccessBiodegradable reduce expenditure bioreactor for augmented sonodynamic therapy via regulating tumor hypoxia and inducing pro-death autophagy
Sonodynamic therapy (SDT) as an emerging reactive oxygen species (ROS)-mediated antitumor strategy is challenged by the rapid depletion of oxygen, as well as the hypoxic tumor microenvironment. Instead of the ...
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Article
Open AccessEffect of acupuncture at Zusanli (ST36) point on antral contraction function under ultrasound guidance: study protocol of a randomized controlled trial
Although the relationship between deqi sensations and curative effect has always been controversial, deqi sensations has been regarded as the key indicator of clinical efficacy of acupuncture therapy. There is li...
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Article
Ultrasound lymphatic imaging for the diagnosis of metastatic central lymph nodes in papillary thyroid cancer
Up to 40% of papillary thyroid cancer (PTC) patients have lymph node metastasis, a condition that implies persistent, recurrent, or progressive disease. However, the American Joint Committee on Cancer Manual stat...
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Article
Open AccessNeutrophil-mediated clinical nanodrug for treatment of residual tumor after focused ultrasound ablation
The risk of local recurrence after high-intensity focused ultrasound (HIFU) is relatively high, resulting in poor prognosis of malignant tumors. The combination of HIFU with traditional chemotherapy continues ...
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Article
Open AccessSelf-synergistic effect of Prussian blue nanoparticles for cancer therapy: driving photothermal therapy and reducing hyperthermia-induced side effects
Photothermal therapy (PTT), involving application of localized hyperthermia to kill cancer cells, has attracted wide attention in cancer therapy. The production of reactive oxygen species (ROS) during PTT may ...
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Article
Open AccessMagnetic nanoparticle-promoted droplet vaporization for in vivo stimuli-responsive cancer theranostics
The development of efficient strategies for in vivo stimuli-responsive cancer treatment and personalized biomedicine is a great challenge. To overcome the critical issues and limitations of traditional protocols ...
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Article
A glassy carbon electrode modified with an amphiphilic, electroactive and photosensitive polymer and with multi-walled carbon nanotubes for simultaneous determination of dopamine and paracetamol
The article describes an electrochemical sensor for simultaneous determination of dopamine (DA) and paracetamol (PAT). It is based on the use of an electroactive polymer (referred to as BPVCM) to functionalize...
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Chapter
Next-Generation Ultrasonic Theranostic Agents for Molecular Imaging and Therapy: Design, Preparation, and Biomedical Application
Ultrasound contrast agents (UCAs) such as microbubbles can oscillate and vibrate when a sonic energy field is applied, making them several thousand times more reflective than normal body tissues and emitting s...
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Article
Open AccessDouble-scattering/reflection in a Single Nanoparticle for Intensified Ultrasound Imaging
Ultrasound contrast agents (UCAs) designed by the conventional composition-based strategy, often suffer from relatively low ultrasound utilization efficiency. In this report, a structure-based design concept o...
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Article
Open AccessEvaluation of superparamagnetic iron oxide-polymer composite microcapsules for magnetic resonance-guided high-intensity focused ultrasound cancer surgery
Superparamagnetic poly (lactic-co-glycolic acid) (PLGA)-coated Fe3O4 microcapsules are receiving increased attention as potential diagnostic and therapeutic modalities in the field of oncology. In this study, PLG...
