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Chapter
Dopamine Receptors in the Gastrointestinal Tract
Dopamine (DA) regulates physiological functions through dopamine receptors (DARs), including D1, D2, D3, D4, and D5. All of the five subtypes mediate neuronal and non-neuronal functions in the central nervous sys...
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Chapter
MicroRNA Biomarkers for Stroke
Stroke is one of the leading cause of death and major cause of long-term disability in the United States. Over years, extensive efforts have been focusing on the development and improvement of diagnostic and t...
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Chapter
Hearing Outcomes After Stereotactic Radiosurgery for Vestibular Schwannomas
The use of stereotactic radiosurgery (SRS) expanded to include the treatment of vestibular schwannomas (VSs) in 1969; since then, efforts to increase tumour control and to reduce cranial neuropathy have contin...
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Chapter
Transplantation of Adipose-Derived Stem Cells in Stroke
Not only is stroke second only to cardiac ischemia as a leading cause of death worldwide, but it also drastically impaired the quality of life of the survivors through its crippling neurological sequelae which...
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Chapter and Conference Paper
Zinc Modulation of Calcium-Permeable AMPA Receptors on Carp Retinal Horizontal Cells
Calcium-permeable AMPA receptors are proved to be expressed on carp retinal horizontal cells. However, the synaptic contribution and modulatory characteristics of these receptors in the synapses between cones ...
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Chapter
Outcome Evaluation in Decision Making: ERP Studies
Decision making can be regarded as an outcome of mental processes (cognitive process) leading to the selection of a course of action among several alternatives. Every decision-making process produces a final c...
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Chapter
PKC and Insulin Pathways in Memory Storage: Targets for Synaptogenesis, Anti-apoptosis, and the Treatment of AD
Long-term memory is stored through the activation of protein kinase C (PKC) isozymes α and ε that interact with insulin pathways in the brain, as well as through the PKC-mediated formation of structurally spec...
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Chapter and Conference Paper
Noise-Induced Coherence Resonance in Morris-Lecar Neuron System
Noise-induced coherence resonance of square coupled ML neuron models is studied. It is found that an intermediate level noise can make the system produce ordered structure. There also exist optimal fluctuation...
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Chapter
Synthetic studies of farnesyl protein transferase inhibitor pepticinnamin E
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Chapter
Synthesis of human inhibin fragments, preparation and generation of monoclonal antibodies against human inhibin
Several hybridoma cell lines which can secret inhibin McAb were obtained with their high specificity and sensitivity, also with their different titer. These studies were important bases for the further syudy—t...
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Chapter
Study of one type of metallothionein and SZ51 recombinant protein directing and imaging reagent
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Chapter
Application of DEPBT for the synthesis of N-protected peptide alcohols
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Chapter
Regulation of Motor Behavior by Dopamine Receptor Subtypes
The neurotransmitter dopamine mediates various behavioral functions in the central nervous system (CNS). The major dopamine pathway involved in motor function is the nigrostriatal pathway, which originates fro...
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Chapter
Electrophysiological Consequences of D2 and/or D3 Receptor Knockout by Antisense Oligonucleotides in Nigrostriatal Dopaminergic Neurons
Mesencephalic dopaminergic neurons possess receptors for their own neurotransmitter, dopamine, at both somatodendritic as well as axon terminal regions. These receptors are termed autoreceptors and act to modu...
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Chapter
Neuropharmacological Effects of (−)-Stepholidine and its Analogues on Brain Dopaminergic System
Tetrahydroprotoberberines (THPBs), a series of natural products isolated from the Chinese herbs Corydalis and Stephania, have been proven to be novel dopamine (DA) receptor antagonists, among them, (-)-stephol...