116 Result(s)
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Chapter
Biosensing Technologies for Detection of Extracellular Vesicles
Extracellular vesicles (EVs) are novel biomarkers evaluated during liquid biopsy and are involved in many physiological functions in cells as well as various pathological processes in diseases. There is an urg...
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Chapter
Histopathology of Hereditary Diffuse Gastric Cancer: From Grossing and 3D Microscopy to Immunophenotypic and Molecular Profiling
Hereditary diffuse gastric cancer (HDGC) is one of the three inherited syndromes that affect primarily the stomach, besides gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) and familial int...
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Chapter and Conference Paper
Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Stress and Promotes ER Protein Degradation in Cyclic Nucleotide-Gated Channel Deficiency
The cone photoreceptor cyclic nucleotide-gated (CNG) channel plays a pivotal role in cone phototransduction. Mutations in genes encoding the channel subunits CNGA3 and CNGB3 account for about 80% of all cases ...
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Chapter
Hepatitis E Virus Life Cycle
Hepatitis E virus (HEV) infects over 20 million people worldwide per year, leading to 30,000–40,000 deaths. In most cases HEV infection in a self-limited, acute illness. However, chronic infections could occur...
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Chapter
The Ergonomic System for the Partial Pressure Suit
In this research, a set of ergonomics evaluation system suitable for the design of high-altitude partial pressure suits has been developed. In this experiment, 21 Chinese men were tested on three ergonomic ind...
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Chapter
Signal Transduction in Acupoints
In the past few decades, scholars on acupuncture mechanisms have studied the characteristics of acupuncture points from the perspectives of anatomical structure, chemical elements, physical properties, physiol...
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Chapter
Study on the Strength of Manual Work
Objective: To investigate the influence of low temperature and low pressure on grip strength and fatigue when wearing extravehicular activity (EVA) gloves. Methods: 10 healthy male participants were asked to w...
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Chapter
ILC Differentiation from Progenitors in the Bone Marrow
Innate lymphoid cells (ILCs) are a family of immune cells that possess similar functions as T cells. We review steps of central ILC development in the bone marrow of adult mice and discuss recent evidence for ...
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Chapter
Fundamentals of Optical Imaging
Optical imaging, which possesses noninvasive and high-resolution features for biomedical imaging, has been used to study various biological samples, from in vitro cells, ex vivo tissue, to in vivo imaging of l...
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Chapter
Astroglia Abnormalities in Post-stroke Mood Disorders
Stroke is the leading cause of human death and disability. After a stroke, many patients may have some physical disability, including difficulties in moving, speaking, and seeing, but patients may also exhibit...
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Chapter
Additive Manufacturing Technologies Based on Photopolymerization
The rapid progress of additive manufacturing (AM) allows the digital design and rapid prototy** of three-dimensional (3D) microstructures, which have promoted the development of optics, electronics, mechanic...
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Chapter
The Cardiovascular Effects of Hydrogen Sulfide: The Epigenetic Mechanisms
Hydrogen sulfide (H2S), known as a gas signal molecule, plays an important role in the development of cardiovascular diseases (CVD) through mechanisms such as angiogenesis, vasodilation, and anti-vascular endothe...
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Chapter
Lipid Metabolism in Tumor-Associated Myeloid-Derived Suppressor Cells
Myeloid-derived suppressor cells (MDSCs) are a heterogenous population of myeloid cells with immature phenotypes and immunosuppressive functions. This population of cells has been extensively studied over the ...
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Chapter
The Applications of the Recellularization Organs in Organ Replacement at the Stage of Animal Research
Organ transplantation is the best treatment option for patients with end-stage organ failure. Unfortunately, the availability of donor organs and immune rejection severely limited organ transplantation, which ...
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Chapter
Functional Neuroanatomy of Salicylate- and Noise-Induced Tinnitus and Hyperacusis
Tinnitus and hyperacusis are debilitating conditions often associated with aging or exposure to intense noise or ototoxic drugs. One of the most reliable methods of inducing tinnitus is with high doses of sodi...
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Chapter
AMD Genetics: Methods and Analyses for Association, Progression, and Prediction
Age-related macular degeneration (AMD) is a multifactorial neurodegenerative disease, which is a leading cause of vision loss among the elderly in the developed countries. As one of the most successful example...
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Chapter
Coronaviruses as Vaccine Vectors for Veterinary Pathogens
Coronaviruses (CoVs, family Coronaviridae) are enveloped, plus-stranded RNA viruses that can cause highly contagious upper respiratory diseases in humans and animals with potentially fatal outcomes. Typical sympt...
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Chapter
“Network Target” Theory and Network Pharmacology
In the biomedical big data and artificial intelligence era, pioneering interdisciplinary information science research, life science, and medicine are represented by a complex biological network which has attra...
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Chapter
Electrophysiological Map** and Source Imaging
In this chapter, we present the physical and physiological basics behind EEG and MEG signal generation and propagation. We first start by presenting the biophysical principles that explain how the coordinated ...
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Chapter
Exercise and Cystic Fibrosis
Cystic fibrosis (CF) is an autosomal recessive, inherited congenital disease caused by the mutation of the family autosomal CF gene, with cumulative exocrine secretion characterized by inflammation, tracheal r...