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  1. No Access

    Article

    Enrichment of Functional Characteristics in the Okara by the Fermentation of Rhizopus azygosporus

    Okara is a solid waste of soybean-processed foods; it is normally used as a low-priced product, such as fertiliser and feed. An alternative method for the convertion of okara to valorized products is required.

    Chun-Yi Hu, Mei-Chen Chiu, Rhytia Ayu Christianty in Waste and Biomass Valorization (2022)

  2. Article

    Open Access

    Novel purification method and antibiotic activity of recombinant Momordica charantia MAP30

    Ribosome-inactivating proteins (RIPs) are a group of enzymes originally isolated from plants that possess the ability to damage ribosomes in an irreversible manner, leading to inhibition of protein synthesis i...

    Ching-Dong Chang, **-Yuan Lin, Yo-Chia Chen, Han-Hsiang Huang, Wen-Ling Shih in 3 Biotech (2017)

  3. Article

    Open Access

    RhoA/ROCK1 regulates Avian Reovirus S1133-induced switch from autophagy to apoptosis

    Autophagy is an essential process in the control of cellular homeostasis. It enables cells under certain stress conditions to survive by removing toxic cellular components, and may protect cells from apoptosis...

    **-Yuan Lin, Ching-Dong Chang, Yo-Chia Chen, Wen-Ling Shih in BMC Veterinary Research (2015)

  4. No Access

    Article

    Avian reovirus S1133-induced apoptosis is associated with Bip/GRP79-mediated Bim translocation to the endoplasmic reticulum

    In this study the mechanism of avian reovirus (ARV) S1133-induced pathogenesis was investigated, with a focus on the contribution of ER stress to apoptosis. Our results showed that upregulation of the ER stres...

    **-Yuan Lin, Hung-Jen Liu, Ching-Dong Chang, Yo-Chia Chen, Chi-I Chang in Apoptosis (2015)

  5. Article

    Open Access

    A highly efficient β-glucosidase from the buffalo rumen fungus Neocallimastix patriciarum W5

    Cellulose, which is the most abundant renewable biomass on earth, is a potential bio-resource of alternative energy. The hydrolysis of plant polysaccharides is catalyzed by microbial cellulases, including endo...

    Hsin-Liang Chen, Yo-Chia Chen, Mei-Yeh Jade Lu, Jui-Jen Chang in Biotechnology for Biofuels (2012)

  6. Article

    Open Access

    Functional characterization of cellulases identified from the cow rumen fungus Neocallimastix patriciarum W5 by transcriptomic and secretomic analyses

    Neocallimastix patriciarum is one of the common anaerobic fungi in the digestive tracts of ruminants that can actively digest cellulosic materials, and its cellulases have great potential for hydrolyzing cellulos...

    Tzi-Yuan Wang, Hsin-Liang Chen, Mei-Yeh J Lu, Yo-Chia Chen in Biotechnology for Biofuels (2011)

  7. No Access

    Article

    The identification, purification, and characterization of STXF10 expressed in Streptomyces thermonitrificans NTU-88

    Multiple xylanolytic enzymes of Streptomyces thermonitrificans NTU-88 were induced by oat-spelt xylan and separated by two-dimensional polyacrylamide and zymogram gels. Nineteen clear spots differed in pI and mol...

    Hsueh-Ling Cheng, Chih-Yun Tsai, Hui-Jye Chen in Applied Microbiology and Biotechnology (2009)

  8. No Access

    Article

    Characterization of the activities of p21Cip1/Waf1 promoter-driven reporter systems during camptothecin-induced senescence-like state of BHK-21 cells

    It was attempted in this work to establish a cell line in which senescent cells can be readily and directly identified in situ in live culture. Transcriptional activation of p21Cip1/Waf1 gene is known to be one o...

    Hsueh-Ling Cheng, Shiou-Ming Chang, Ya-Wen Cheng in Molecular and Cellular Biochemistry (2006)

  9. No Access

    Article

    Immunogold labeling of CM-cellulase in Sinorhizobium fredii CCRC15769 by electron microscopy

    The symbiotic roles of rhizobia with legumes have been extensively made use of in the agricultural field. An unresolved question about the infection process is the nature of the Rhizobium enzymes that degrade the...

    Chun-Yi Hu, Shu-Ling Hsieh, Jaang J. Wang in World Journal of Microbiology and Biotechn… (2006)