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  1. Article

    Open Access

    DEGS2 polymorphism associated with cognition in schizophrenia is associated with gene expression in brain

    A genome-wide association study of cognitive deficits in patients with schizophrenia in Japan found association with a missense genetic variant (rs7157599, Asn8Ser) in the delta(4)-desaturase, sphingolipid 2 (DEG...

    K Ohi, G Ursini, M Li, J H Shin, T Ye, Q Chen, R Tao… in Translational Psychiatry (2015)

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  2. No Access

    Article

    Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain

    Dopamine 2 receptor (DRD2) is of major interest to the pathophysiology of schizophrenia (SCZ) both as a target for antipsychotic drug action as well as a SCZ-associated risk gene. The dopamine 1 receptor (DRD1...

    S S Kaalund, E N Newburn, T Ye, R Tao, C Li, A Deep-Soboslay… in Molecular Psychiatry (2014)

  3. No Access

    Article

    Revisiting DARPP-32 in postmortem human brain: changes in schizophrenia and bipolar disorder and genetic associations with t-DARPP-32 expression

    Dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa (DARPP-32 or PPP1R1B) has been of interest in schizophrenia owing to its critical function in integrating dopaminergic and glutaminergic sign...

    Y Kunii, T M Hyde, T Ye, C Li, B Kolachana, D Dickinson… in Molecular Psychiatry (2014)

  4. Article

    Open Access

    Interactions of human truncated DISC1 proteins: implications for schizophrenia

    Numerous genetic linkage and association reports have implicated the Disrupted-in-Schizophrenia (DISC1) gene in psychiatric illness. The Scottish family translocation, predicted to encode a C-terminus-truncated p...

    E N Newburn, T M Hyde, T Ye, Y Morita, D R Weinberger… in Translational Psychiatry (2011)

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