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  1. Article

    Open Access

    Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples

    Sensitive and specific blood-based assays for the detection of pulmonary and extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses, particularly in children. Here we report a nano...

    Wenshu Zheng, Sylvia M. LaCourse, Bofan Song in Nature Biomedical Engineering (2022)

  2. Article

    Open Access

    Evaluation of a serum-based antigen test for tuberculosis in HIV-exposed infants: a diagnostic accuracy study

    Non-sputum methods are urgently needed to improve tuberculosis diagnosis and treatment monitoring in children. This study evaluated the ability of a serum assay quantifying a species-specific peptide of the Mycob...

    Liyan Mao, Sylvia M. LaCourse, Soyeon Kim, Chang Liu, Bo Ning, Duran Bao in BMC Medicine (2021)

  3. Article

    Open Access

    Pulmonary tuberculosis screening in anti-retroviral treated adults living with HIV in Kenya

    People living with HIV (PLHIV) who reside in high tuberculosis burden settings remain at risk for tuberculosis disease despite treatment with anti-retroviral therapy and isoniazid preventive therapy (IPT). The...

    Jill K. Gersh, Ruanne V. Barnabas, Daniel Matemo, John Kinuthia in BMC Infectious Diseases (2021)

  4. No Access

    Article

    HIV Testing and Epidemiology in a Hospital-Based Surgical Cohort in Malawi

    Despite the high prevalence of HIV in adults (11 %) in Malawi, testing among surgical patients is not routine. We examined the feasibility of universal opt-out HIV testing and counseling (HTC) on the surgical ...

    Bryce E. Haac, Anthony G. Charles, Mitch Matoga in World Journal of Surgery (2013)