32 Result(s)

Article

Correction: Undernutrition in young children with congenital heart disease undergoing cardiac surgery in a low‑income environment

Robyn Smith, Veronica Ntsiea, Stephen Brown, Joanne Potterton in BMC Pediatrics (2024)

Article

Impairment in sleep health in young adults with chronic pain: a modifiable risk factor

Impairments in sleep health are associated with the development or worsening of chronic pain. Further, chronic pain can cause sleep health disruption by impacting sleep onset, sleep maintenance, sleep quality,...

Mohamed Eissa, Anuj Bhatia, Shikha Bansal, Tania Di Renna… in Sleep Science and Practice (2023)

Article

Boosting neuregulin 1 type-III expression hastens SMA motor axon maturation

Intercellular communication between axons and Schwann cells is critical for attaining the complex morphological steps necessary for axon maturation. In the early onset motor neuron disease spinal muscular atro...

Lingling Kong, Cera W. Hassinan, Florian Gerstner… in Acta Neuropathologica Communications (2023)

Article

Improved constraints on effective top quark interactions using edge convolution networks

We explore the potential of Graph Neural Networks (GNNs) to improve the performance of high-dimensional effective field theory parameter fits to collider data beyond traditional rectangular cut-based different...

Oliver Atkinson, Akanksha Bhardwaj, Stephen Brown… in Journal of High Energy Physics (2022)

Article

The Rise and Fall of the Aid Effectiveness Norm

This article analyzes the rise and fall of the aid effectiveness norm, using the lens of Finnemore and Sikkink’s norm ‘life cycle’. I argue that, although donors and recipients endorsed the founding principles...

Stephen Brown in The European Journal of Development Research (2020)

Article

The Use of Computer Simulation Modeling to Estimate Complications in Patients with Type 2 Diabetes Mellitus: Comparative Validation of the Cornerstone Diabetes Simulation Model

The objective of this study was to assess the validity of the Cornerstone Diabetes Simulation (CDS), a Microsoft Excel^®-based patient-level simulation for type 2 diabetes mellitus based on risk equations from the...

Zhuo T. Su, Jose Bartelt-Hofer, Stephen Brown, Elisheva Lew… in PharmacoEconomics - Open (2020)

Article

Comprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks

Long non-coding RNAs (lncRNAs) are emerging as crucial regulators of cellular processes in diseases such as cancer, although the functions of most remain poorly understood. To address this, here we apply a nov...

Kevin Walters, Radmir Sarsenov, Wen Siong Too, Roseanna K. Hare… in BMC Genomics (2019)

Article

Kinetic modeling of tumor regression incorporating the concept of cancer stem-like cells for patients with locally advanced lung cancer

Personalized medicine for patients receiving radiation therapy remains an elusive goal due, in part, to the limits in our understanding of the underlying mechanisms governing tumor response to radiation. The p...

Hualiang Zhong, Stephen Brown… in Theoretical Biology and Medical Modelling (2018)

Article

The Hiperwall tiled-display wall system for Big-Data research

In the era of Big Data, with the increasing use of large-scale data-driven applications, visualization of very large high-resolution images and extracting useful information (searching for specific targets or ...

Muhammad Saleem, Hugo E. Valle, Stephen Brown, Veronica I. Winters… in Journal of Big Data (2018)

Article

ACTA2 mutation and postpartum hemorrhage: a case report

ACTA2 encodes smooth muscle specific α-actin, a critical component or the contractile complex of vascular smooth muscle. Mutations in ACTA2 are the most common genetic cause of thoraci...

Kylie Cooper, Stephen Brown in BMC Medical Genetics (2017)

Article

Re-examining the ECB’s two-pillar monetary policy strategy: Are there any deviations during and the pre-financial crisis periods?

This paper addresses the extent to which the ECB rate setting responded to inflation and monetary growth in the run up to, and during, the financial crisis of the late 2000s. The analysis covers the period bet...

Ahmad Hassan Ahmad, Stephen Brown in Empirica (2017)

Article

Shaped by asymmetrical interdependence: a qualitative case study of the external influences on international non-governmental organizations´ implementation of equity principles in HIV/AIDS work

Addressing inequities is a key role for international non-governmental organizations (INGOs) working in health and development. Yet, putting equity principles into practice can prove challenging. In-depth empi...

Elizabeth Dyke, Nancy Edwards, Ian McDowell… in International Journal for Equity in Health (2014)

Article

A Microsoft-Excel-based tool for running and critically appraising network meta-analyses—an overview and application of NetMetaXL

The use of network meta-analysis has increased dramatically in recent years. WinBUGS, a freely available Bayesian software package, has been the most widely used software package to conduct network meta-analys...

Stephen Brown, Brian Hutton, Tammy Clifford, Doug Coyle, Daniel Grima… in Systematic Reviews (2014)

Article

NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials

HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection. NGX-4010 is a capsaicin 8% dermal patch with demonstrated efficacy ...

Stephen Brown, David M Simpson, Graeme Moyle, Bruce J Brew… in AIDS Research and Therapy (2013)

Article

Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway

Genome-scale RNA-interference (RNAi) screens are becoming ever more common gene discovery tools. However, whilst every screen identifies interacting genes, less attention has been given to how factors such as ...

Katherine H Fisher, Victoria M Wright, Amy Taylor, Martin P Zeidler… in BMC Genomics (2012)