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Article
Open AccessChanges in the gut microbiome community of nonhuman primates following radiation injury
Composition and maintenance of the microbiome is vital to gut homeostasis. However, there is limited knowledge regarding the impact of high doses of radiation, which can occur as a result of cancer radiation t...
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Article
Open AccessThe vaccinia virus based Sementis Copenhagen Vector vaccine against Zika and chikungunya is immunogenic in non-human primates
The Sementis Copenhagen Vector (SCV) is a new vaccinia virus-derived, multiplication-defective, vaccine technology assessed herein in non-human primates. Indian rhesus macaques (Macaca mulatta) were vaccinated wi...
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Article
Open AccessComprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks
Long non-coding RNAs (lncRNAs) are emerging as crucial regulators of cellular processes in diseases such as cancer, although the functions of most remain poorly understood. To address this, here we apply a nov...
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Protocol
Epigenetic Variation
Epigenetics is a fast moving field and our understanding of epigenetic mechanisms has dramatically improved in recent decades. We present the role that epigenetics plays in genomic control in humans; the molec...
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Article
The effect of genoty** error in sib-pair genomewide linkage scans depends crucially upon the method of analysis
In genomewide linkage scans for complex diseases involving many loci with small genetic effects, it may be the case that no loci reach conventional statistical significance. A complementary method of evaluatin...
