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  1. Article

    Open Access

    Comprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks

    Long non-coding RNAs (lncRNAs) are emerging as crucial regulators of cellular processes in diseases such as cancer, although the functions of most remain poorly understood. To address this, here we apply a nov...

    Kevin Walters, Radmir Sarsenov, Wen Siong Too, Roseanna K. Hare in BMC Genomics (2019)

  2. No Access

    Article

    Physiological characterization of the high malic acid-producing Aspergillus oryzae strain 2103a-68

    Malic acid is a C4 dicarboxylic acid that is currently mainly used in the food and beverages industry as an acidulant. Because of the versatility of the group of C4 dicarboxylic acids, the chemical industry has a...

    Christoph Knuf, Intawat Nookaew, Ilse Remmers in Applied Microbiology and Biotechnology (2014)

  3. Article

    Open Access

    Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway

    Genome-scale RNA-interference (RNAi) screens are becoming ever more common gene discovery tools. However, whilst every screen identifies interacting genes, less attention has been given to how factors such as ...

    Katherine H Fisher, Victoria M Wright, Amy Taylor, Martin P Zeidler in BMC Genomics (2012)