![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessRelationship between amyloid and tau levels and its impact on tau spreading
Previous studies have shown that Aβ-amyloid (Aβ) likely promotes tau to spread beyond the medial temporal lobe. However, the Aβ levels necessary for tau to spread in the neocortex is still unclear.
-
Article
Open AccessInsulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults
Growing evidence supports the hypothesis that type 2 diabetes (T2D) increases the risk of develo** dementia. Experimental evidence from mouse models demonstrates that the induction of T2D/insulin resistance ...
-
Article
Open AccessFollow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort
Alzheimer’s disease (AD) is a growing socioeconomic problem worldwide. Early diagnosis and prevention of this devastating disease have become a research priority. Consequently, the identification of clinically...