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  1. No Access

    Article

    Expression of LC3B and FIP200/Atg17 in brain metastases of breast cancer

    Macroautophagy/autophagy is considered to play key roles in tumor cell evasion of therapy and establishment of metastases in breast cancer. High expression of LC3, a residual autophagy marker, in primary breas...

    Nooshin Hashemi-Sadraei, Gaëlle M. Müller-Greven… in Journal of Neuro-Oncology (2018)

  2. No Access

    Article

    Hypomethylation of the MMP7 promoter and increased expression of MMP7 distinguishes the basal-like breast cancer subtype from other triple-negative tumors

    Identification of novel targets for the treatment of basal-like breast cancer is essential for improved outcomes in patients with this disease. This study investigates the association of MMP7 expression and MMP7 ...

    Steven T. Sizemore, Gina M. Sizemore… in Breast Cancer Research and Treatment (2014)

  3. No Access

    Article

    Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-β signaling in ErbB2/Neu-induced tumors from transgenic mice

    Upregulation of HER2/ErbB2/Neu occurs in 15–30% of human breast cancers and correlates with poor prognosis. Identification of ErbB2/Neu transcriptional targets should facilitate development of novel therapeuti...

    Melissa D Landis, Darcie D Seachrist, Marjorie E Montañez-Wiscovich… in Oncogene (2005)

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    Article

    High levels of luteinizing hormone analog stimulate gonadal and adrenal tumorigenesis in mice transgenic for the mouse inhibin-α-subunit promoter/Simian virus 40 T-antigen fusion gene

    Transgenic (TG) mice expressing the Simian virus 40 T-antigen under the control of the murine inhibin-α promoter (Inhα/Tag) develop granulosa and Leydig cell tumors at the age of 5–6 months, with 100% penetrance....

    Maarit Mikola, Jukka Kero, John H Nilson, Ruth A Keri, Matti Poutanen… in Oncogene (2003)