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  1. No Access

    Article

    TGF-β/SMAD Pathway Mediates Cadmium Poisoning-Induced Chicken Liver Fibrosis and Epithelial-Mesenchymal Transition

    Cadmium(Cd) is a toxic heavy metal widely present in the environment, capable of accumulating in the liver and causing liver damage. In this study, the mechanism of cadmium-induced liver fibrosis in chickens w...

    **yang Zhang, Yiming Sun, Miao Yu, Yihan Hu in Biological Trace Element Research (2024)

  2. Article

    Open Access

    Iron-based metal-organic framework co-loaded with buthionine sulfoximine and oxaliplatin for enhanced cancer chemo-ferrotherapy via sustainable glutathione elimination

    Emerging ferroptosis-driven therapies based on nanotechnology function either by increasing intracellular iron level or suppressing glutathione peroxidase 4 (GPX4) activity. Nevertheless, the therapeutic strat...

    Zhi** Rao, Yutian **a, Qian Jia, Yutong Zhu, Lexuan Wang in Journal of Nanobiotechnology (2023)

  3. No Access

    Article

    Selenium Deficiency Induces Autophagy in Chicken Bursa of Fabricius Through ChTLR4/MyD88/NF-κB Pathway

    To explore the role of ChTLR4/MyD88/NF-κB signaling pathway on autophagy induced by selenium (Se) deficiency in the chicken bursa of Fabricius, autophagosome formation in the bursa of Fabricius was observed by...

    Ruili Zhang, Qing Liu, Rong Guo, Di Zhang, Yang Chen in Biological Trace Element Research (2022)

  4. Article

    Selenium Deficiency Causes Inflammatory Injury in the Bursa of Fabricius of Broiler Chickens by Activating the Toll-like Receptor Signaling Pathway

    The aim of our study was to observe the effect of selenium (Se) deficiency on inflammatory injury in the bursa of Fabricius of broiler chickens and to determine the role of the Toll-like receptor (TLR)/myeloid...

    Yu Bai, Ruili Zhang, Qing Liu, Rong Guo, Guangxing Li in Biological Trace Element Research (2022)

  5. No Access

    Article

    Astragalus Polysaccharide Protects Against Cadmium-Induced Autophagy Injury Through Reactive Oxygen Species (ROS) Pathway in Chicken Embryo Fibroblast

    Cadmium (Cd) is a harmful heavy metal pollutant, which can cause oxidative stress in the body and induce cell damage. Reactive oxygen species (ROS) is a general term for substances that contain oxygen and are ...

    Xudong Shen, Zequn Tang, Yu Bai, Meishuo Wan, Miao Yu in Biological Trace Element Research (2022)

  6. No Access

    Article

    Selenium Deficiency via the TLR4/TRIF/NF-κB Signaling Pathway Leading to Inflammatory Injury in Chicken Spleen

    The aim of the present study was to investigate the effect of selenium (Se) deficiency on the expression of the toll-like receptor (TLR) signal transduction pathway in the spleen of chickens and explore the re...

    Ruili Zhang, Rong Guo, Qing Liu, Guangxing Li, Bin Sun in Biological Trace Element Research (2021)

  7. No Access

    Article

    Effects of Fungal Polysaccharide on Oxidative Damage and TLR4 Pathway to the Central Immune Organs in Cadmium Intoxication in Chickens

    Cadmium (Cd) can cause animal organism damage, but there have been few studies on the damage of cadmium to the immune organs of birds. Most fungal polysaccharide has antioxidant and immunomodulatory effects. T...

    Ruyue Li, Linan Zhang, Zequn Tang, Tianqi Li in Biological Trace Element Research (2019)

  8. No Access

    Article

    Protective Effect of Ganoderma Triterpenoids on Cadmium-Induced Testicular Toxicity in Chickens

    Studies have shown that cadmium can cause chicken testicular damage, but a protective effect of Ganoderma triterpenoids on cadmium-induced testicular damage in chickens has not yet been reported. The present s...

    Hongmei Wang, Ruili Zhang, Yangyang Song, Tianqi Li in Biological Trace Element Research (2019)

  9. No Access

    Article

    Protective Effect of Agaricus blazei Polysaccharide Against Cadmium-Induced Damage on the Testis of Chicken

    Cadmium (Cd) exposure can cause reproductive toxicity through oxidative stress and inflammatory response. A polysaccharide extract of the edible mushroom Agaricus blazei Murill has been isolated and exhibits anti...

    Yangyang Song, Ruili Zhang, Hongmei Wang, Yan Yan in Biological Trace Element Research (2018)

  10. No Access

    Article

    Agaricus blazei Murill Polysaccharides Protect Against Cadmium-Induced Oxidative Stress and Inflammatory Damage in Chicken Spleens

    Agaricus blazei Murill polysaccharide (ABP) has exhibited antioxidant and immunoregulatory activity. The aim of this study was to investigate the effect of ABP on cadmium (Cd)-induced antioxidant...

    Wanqiu **e, Ai Lv, Ruyue Li, Zequn Tang, Dexing Ma in Biological Trace Element Research (2018)

  11. No Access

    Article

    Effects of Agaricus blazei Murill Polysaccharide on Cadmium Poisoning on the MDA5 Signaling Pathway and Antioxidant Function of Chicken Peripheral Blood Lymphocytes

    This experimental study investigated the effect of Agaricus blazei Murill polysaccharide (ABP) on cadmium (Cd) poisoning on the melanoma differentiation-associated gene 5 (MDA5) signaling pathway and antioxidant ...

    Ai Lv, Ming Ge, Xuequan Hu, Wen**g Liu, Guangxing Li in Biological Trace Element Research (2018)

  12. Article

    Open Access

    Effects of soybean meal fermented by L. plantarum, B. subtilis and S. cerevisieae on growth, immune function and intestinal morphology in weaned piglets

    The present study compared the effects of soybean meal fermented by three different probiotics organisms with non-fermented soybean meal on growth performance, serum parameters, immune chemistry and intestinal...

    Jiajia Zhu, Mingxing Gao, Ruili Zhang, Zhuojian Sun in Microbial Cell Factories (2017)

  13. No Access

    Article

    The Effects of Agaricus blazei Murill Polysaccharides on Cadmium-Induced Apoptosis and the TLR4 Signaling Pathway of Peripheral Blood Lymphocytes in Chicken

    In this study, we investigated the effects of Agaricus blazei Murill polysaccharides (ABP) on cadmium (Cd)-induced apoptosis and the TLR4 signaling pathway of chicken peripheral blood lymphocytes (PBLs). Seven-da...

    Wen**g Liu, Ming Ge, Xuequan Hu, Ai Lv, Dexing Ma in Biological Trace Element Research (2017)

  14. No Access

    Article

    The Protective Effects of Polysaccharides from Agaricus blazei Murill Against Cadmium-Induced Oxidant Stress and Inflammatory Damage in Chicken Livers

    This study aimed to assess the protective roles of polysaccharides from Agaricus blazei Murill (ABP) against cadmium (Cd)-induced damage in chicken livers. A total of 80 Hy-Line laying chickens (7 days old) were ...

    Xuequan Hu, Ruili Zhang, Yingying **e, Hongmei Wang in Biological Trace Element Research (2017)