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    Article

    Streamlining Food Effect Assessment — Are Repeated Food Effect Studies Needed? An IQ Analysis

    Current regulatory guidelines on drug-food interactions recommend an early assessment of food effect to inform clinical dosing instructions, as well as a pivotal food effect study on the to-be-marketed formula...

    Filippos Kesisoglou, Sumit Basu, Tejashree Belubbi, Philip Bransford in The AAPS Journal (2023)

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    Open Access

    Role of miR-182/PDCD4 axis in aggressive behavior of prostate cancer in the African Americans

    Prostate cancer is one of the most commonly diagnosed cancers among men. African Americans (AA) are at an increased risk of develo** prostate cancer compared to European Americans (EA). miRNAs play a critica...

    Marisa Shiina, Yutaka Hashimoto, Priyanka Kulkarni, Pritha Dasgupta in BMC Cancer (2021)

  3. Article

    Correction to: Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective

    An Erratum to this paper has been published: https://doi.org/10.1208/s12248-020-00535-z

    Arian Emami Riedmaier, Kevin DeMent, James Huckle, Phil Bransford in The AAPS Journal (2020)

  4. Article

    Open Access

    Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective

    The effect of food on pharmacokinetic properties of drugs is a commonly observed occurrence affecting about 40% of orally administered drugs. Within the pharmaceutical industry, significant resources are inves...

    Arian Emami Riedmaier, Kevin DeMent, James Huckle, Phil Bransford in The AAPS Journal (2020)