47 Result(s)

Article

The impact of intraoperative hypotension on postoperative acute kidney injury, mortality and length of stay following off-pump coronary artery bypass grafting surgery: a single-center retrospective cohort study

Off-pump coronary artery bypass grafting (OPCABG) presents distinct hemodynamic characteristics, yet the relationship between intraoperative hypotension and short-term adverse outcomes remains clear. Our study...

Cheng **ao, Ming Yang, Lei Cao, Fang Chen, Sheng **g, Yuting Tan… in BMC Anesthesiology (2024)

Article

Correlating Reiff scores with clinical, functional, and prognostic factors: characterizing noncystic fibrosis bronchiectasis severity: validation from a nationwide multicenter study in Taiwan

Our study aimed to confirm a simplified radiological scoring system, derived from a modified Reiff score, to evaluate its relationship with clinical symptoms and predictive outcomes in Taiwanese patients with ...

Wen-Chien Cheng, Chia-Ling Chang, Chau-Chyun Sheu… in European Journal of Medical Research (2024)

Article

Loss of LECT2 promotes ovarian cancer progression by inducing cancer invasiveness and facilitating an immunosuppressive environment

Leukocyte cell-derived chemotaxin 2 (LECT2) is a multifunctional cytokine that can bind to several receptors and mediate distinct molecular pathways in various cell settings. Changing levels of LECT2 have been...

Chin-Jui Wu, Ke-Fan Pan, Ji-Qing Chen, Yu -Chen Tao, Yu-Cheng Liu, Bo-Rong Chen… in Oncogene (2024)

Article

Interleukin-4 Modulates Neuroinflammation by Inducing Phenotypic Transformation of Microglia Following Subarachnoid Hemorrhage

Neuroinflammation, a key pathological feature following subarachnoid hemorrhage (SAH), can be therapeutically targeted by inhibiting microglia M1 polarization and promoting phenotypic transformation to M2 micr...

**g Wang, Lili Wang, Qingjian Wu, Yichen Cai, Chengfu Cui, Ming Yang… in Inflammation (2024)

Article

A real-world case–control study on the efficacy and safety of pulsed field ablation for atrial fibrillation

The primary objective of this study was to evaluate the efficacy and safety of pulsed field ablation in individuals diagnosed with atrial fibrillation.

Ming Yang, Peng-yu Wang, Ying-lu Hao, Mei Liang… in European Journal of Medical Research (2023)

Article

Large common bile duct stones in high-risk elderly patients: Immediate endoscopic stone removal or elective stone removal? A single-center retrospective study

For high-risk elderly patients with chronic diseases, endoscopic stone removal for large common bile duct stones is associated with a high risk of adverse events and incomplete stone removal. The aim of this s...

Ke Meng, Da-ya Zhang, De-xin Chen, Wen-**g Liu, Kai-xuan Fang… in BMC Gastroenterology (2023)

Article

Differential diagnosis of adrenal adenomas and metastases using spectral parameters in dual-layer detector spectral CT

To assess the diagnostic value of spectral parameters in differentiating adrenal adenomas from metastases based on dual-layer detector spectral CT (DLSCT).

Lei-di Wu, **ao-fei Yue, Lin-xia Wu… in Journal of Cancer Research and Clinical On… (2023)

Article

Correction: Non-enzymatic heparanase enhances gastric tumor proliferation via TFEB-dependent autophagy

Min Yang, Bo Tang, Sumin Wang, Li Tang, Dalin Wen, Israel Vlodavsky… in Oncogenesis (2023)

Article

Comparative short-term and survival outcomes of three specimen extraction techniques in laparoscopic low rectal cancer surgery: does it affect ileostomy closure?

This study aimed to compare the short-term and survival outcomes in laparoscopic low rectal cancer surgery with three different specimen extraction techniques, and whether it affects loop ileostomy closure.

Haipeng Chen, Fei Huang, Ming Yang, Zhixun Zhao, Xu Guan, Zheng Liu… in BMC Surgery (2023)

Article

Biomechanical effects of internal fixation with self-lock compression anti-rotation blade for Pauwels type III femoral neck fractures: a comparative finite element analysis

Self-lock compression anti-rotation blade (SCAB) is a novel internal fixation implant for femoral neck fractures (FNF). We conducted this finite element analysis study to evaluate the biomechanical performance...

Bo-Xuan Huang, Si-Zheng Zhan, Ming Yang, Dian-Ying Zhang in BMC Musculoskeletal Disorders (2023)

Article

Characterization of mesenchymal stem cells in human fetal bone marrow by single-cell transcriptomic and functional analysis

Bone marrow mesenchymal stromal/stem cells (MSCs) are a heterogeneous population that can self-renew and generate stroma, cartilage, fat, and bone. Although a significant progress has been made toward recogniz...

** Zhang, Ji Dong, **aoying Fan, Jun Yong… in Signal Transduction and Targeted Therapy (2023)

Article

Safety and immunogenicity of a mosaic vaccine booster against Omicron and other SARS-CoV-2 variants: a randomized phase 2 trial

An ongoing randomized, double-blind, controlled phase 2 trial was conducted to evaluate the safety and immunogenicity of a mosaic-type recombinant vaccine candidate, named NVSI-06-09, as a booster dose in subj...

Nawal Al Kaabi, Yun Kai Yang, Yu Liang, Ke Xu… in Signal Transduction and Targeted Therapy (2023)

Article

A proposed feasible classification of common bile duct duplications based on a newly described variant and review of existing literature

Duplication of the common bile duct (CBD) is extremely rare among the anatomical variations in the biliary tract system, which presents a septum within the CBD or an accessory CBD. In our study, we report a ra...

Huixue Sheng, Guiling Chen, Ming Yang, Hongmei Guan in BMC Pediatrics (2022)

Article

Hidden blood loss and its influencing factors after minimally invasive percutaneous transpedicular screw fixation in thoracolumbar fracture

Minimally invasive percutaneous transpedicular screw fixation (MIPTSF) is generally accepted as a minimally invasive treatment for thoracolumbar fracture. However, hidden blood loss (HBL) caused by this proced...

**n Yue, **g Zhang, Tianze Sun, Wentao Zhang, Ming Yang… in BMC Musculoskeletal Disorders (2022)

Article

Non-enzymatic heparanase enhances gastric tumor proliferation via TFEB-dependent autophagy

Heparanase (HPA) is the predominant enzyme that cleaves heparan sulfate and plays a critical role in a variety of pathophysiological processes. HPA activity has been traditionally correlated with tumor metasta...

Min Yang, Bo Tang, Sumin Wang, Li Tang, Dalin Wen, Israel Vlodavsky… in Oncogenesis (2022)

Article

Occluding morphologically complicated left atrial appendage using the small-umbrella LAmbre device

Percutaneous left atrial appendage (LAA) occlusion is effective for stroke prevention in patients with atrial fibrillation. LAA can have a complex anatomy, such as multiple lobes or a large orifice, which may ...

Hong-Da Zhang, Ming Yang, Yang-Bo **ng, Si-**an Weng… in BMC Cardiovascular Disorders (2022)

Article

Immunogenicity and safety of NVSI-06-07 as a heterologous booster after priming with BBIBP-CorV: a phase 2 trial

The increased coronavirus disease 2019 (COVID-19) breakthrough cases pose the need of booster vaccination. We conducted a randomised, double-blinded, controlled, phase 2 trial to assess the immunogenicity and ...

Nawal Al Kaabi, Yun Kai Yang, **g Zhang, Ke Xu… in Signal Transduction and Targeted Therapy (2022)

Article

Machine Learning to Determine Risk Factors for Myopia Progression in Primary School Children: The Anyang Childhood Eye Study

To investigate the risk factors for myopia progression in primary school children and build prediction models by applying machine learning to longitudinal, cycloplegic autorefraction data.

Shi-Ming Li, Ming-Yang Ren, Jiahe Gan, San-Guo Zhang… in Ophthalmology and Therapy (2022)

Article

miR-146a impedes the anti-aging effect of AMPK via NAMPT suppression and NAD⁺/SIRT inactivation

Nicotinamide adenine dinucleotide (NAD⁺) is indispensable for the anti-aging activity of the sirtuin (SIRT) family enzymes. AMP-activated protein kinase (AMPK) upregulates NAD⁺ synthesis and SIRT activity in a ni...

Hui Gong, Honghan Chen, Peng **ao, Ning Huang… in Signal Transduction and Targeted Therapy (2022)

Article

LncRNAs LCETRL3 and LCETRL4 at chromosome 4q12 diminish EGFR-TKIs efficiency in NSCLC through stabilizing TDP43 and EIF2S1

Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are effective targeted therapy drugs for advanced non-small cell lung cancer (NSCLC) patients carrying sensitized EGFR mutations. The rapi...

Yankang Li, Yue Shen, Mengyu **e, Bowen Wang… in Signal Transduction and Targeted Therapy (2022)