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Open AccessEuropean Network for ICU-Related Respiratory Infections (ENIRRIs): a multinational, prospective, cohort study of nosocomial LRTI
Lower respiratory tract infections (LRTI) are the most frequent infectious complication in patients admitted to the intensive care unit (ICU). We aim to report the clinical characteristics of ICU-admitted pati...
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Correction: ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
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ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
Severe community-acquired pneumonia (sCAP) is associated with high morbidity and mortality, and whilst European and non-European guidelines are available for community-acquired pneumonia, there are no specific...
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Article
Defining basic (lung) ultrasound skills: not so basic after all?
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Open AccessAcute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis
Subphenotypes were recently reported within clinical acute respiratory distress syndrome (ARDS), with distinct outcomes and therapeutic responses. Experimental models have long been used to mimic features of A...
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Article
Mechanical power of ventilation is associated with mortality in critically ill patients: an analysis of patients in two observational cohorts
Mechanical power (MP) may unify variables known to be related to development of ventilator-induced lung injury. The aim of this study is to examine the association between MP and mortality in critically ill pa...
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Article
Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study
To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification.
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Selective decontamination of the digestive tract halves the prevalence of ventilator-associated pneumonia compared to selective oral decontamination
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Will all ARDS patients be receiving mechanical ventilation in 2035? Yes
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High-flow nasal cannula in the postoperative period: is positive pressure the phantom of the OPERA trial?
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Increased incidence of co-infection in critically ill patients with influenza
Co-infection is frequently seen in critically ill patients with influenza, although the exact rate is unknown. We determined the rate of co-infection, the risk factors and the outcomes associated with co-infec...
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External validation confirms the legitimacy of a new clinical classification of ARDS for predicting outcome