32 Result(s)

Article

Transcriptional Complementarity in Breast Cancer: Application to Detection of Circulating Tumor Cells

Background: We used a combination of genetic subtraction, silicon DNA micro-array analysis, and quantitative PCR to identify tissue-and tumor-specific genes as diagnostic targets for breast cance...

Raymond L. Houghton PhD, Davin C. Dillon PhD, David A. Molesh BA… in Molecular Diagnosis (2001)

Article

Preparation and development of equine hyperimmune globulin F(ab′)₂ against severe acute respiratory syndrome coronavirus

The resurgence of severe acute respiratory syndrome (SARS) is still a threat because the causative agent remaining in animal reservoirs is not fully understood, and sporadic cases continue to be reported. Deve...

Jai-hai Lu, Zhong-min Guo, Wen-yu Han, Guo-ling Wang… in Acta Pharmacologica Sinica (2005)

Article

Monoclonal antibodies against the nucleocapsid proteins of henipaviruses: production, epitope map** and application in immunohistochemistry

Four monoclonal antibodies (mAbs) were generated by immunizing BALB/C mice with recombinant nucleocapsid protein (N) of Nipah virus (NiV) and Hendra virus (HeV) expressed in E. coli. Two mAbs each were obtained f...

C. **ao, Y. Liu, Y. Jiang, D. E. Magoffin, H. Guo, H. Xuan, G. Wang… in Archives of Virology (2008)

Article

Genomic analysis of Newcastle disease virus strain NA-1 isolated from geese in China

M. Xu, S. Chang, Z. Ding, H.-W. Gao, J.-Y. Wan, W.-S. Liu… in Archives of Virology (2008)

Article

Trichomonasvirus: a new genus of protozoan viruses in the family Totiviridae

The family Totiviridae includes a number of viruses with monosegmented dsRNA genomes and isometric virions that infect either fungi or a number of medically important protozoan parasites such as Leishmania and Gi...

Russell P. Goodman, Said A. Ghabrial, Raina N. Fichorova… in Archives of Virology (2011)

Article

Erratum to: Sustained and differential antibody responses to virulence proteins of Brucella melitensis during acute and chronic infections in human brucellosis

J. Xu, Y. Qiu, M. Cui, Y. Ke, Q. Zhen… in European Journal of Clinical Microbiology … (2013)

Article

Erratum to: Suppression of MAPK and NF-κB Pathways by Limonene Contributes to Attenuation of Lipopolysaccharide-Induced Inflammatory Responses in Acute Lung Injury

Gefu Chi, Miaomiao Wei, **anxing **e, L. W. Soromou, Fang Liu, Shuhua Zhao in Inflammation (2013)

Article

Comparisons of vaginal and abdominal radical trachelectomy for early-stage cervical cancer: preliminary results of a multi-center research in China

There are limited data comparing the prognosis and fertility outcomes of the patients with early cervical cancer treated by trans-vaginal radical trachelectomy (VRT) or abdominal radical trachelectomy (ART).The o...

D Y Cao, J X Yang, X H Wu, Y L Chen, L Li, K J Liu, M H Cui… in British Journal of Cancer (2013)

Article

HIV-1 Vif N-terminal Motif is required for recruitment of Cul5 to Suppress APOBEC3

HIV-1 Vif promotes the degradation of host anti-retroviral factor family, APOBEC3 proteins via the recruitment of a multi-subunit E3 ubiquitin ligase complex. The complex is composed of a scaffold protein, Cul...

Sean L Evans, Arne Schön, Qimeng Gao, Xue Han, **aohong Zhou… in Retrovirology (2014)

Article

Malignant phyllodes tumors display mesenchymal stem cell features and aldehyde dehydrogenase/disialoganglioside identify their tumor stem cells

Although breast phyllodes tumors are rare, there is no effective therapy other than surgery. Little is known about their tumor biology. A malignant phyllodes tumor contains heterologous stromal elements, and c...

**-** Lin, Chiun-Sheng Huang, John Yu, Guo-Shiou Liao… in Breast Cancer Research (2014)

Article

Elevated expression of myosin X in tumours contributes to breast cancer aggressiveness and metastasis

Myosin X (MYO10) was recently reported to promote tumour invasion by transporting integrins to filopodial tips in breast cancer. However, the role of MYO10 in tumours remains poorly defined. Here, we report th...

R Cao, J Chen, X Zhang, Y Zhai, X Qing, W **ng, L Zhang… in British Journal of Cancer (2014)

Article

The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells

The cell-intrinsic factors that regulate the differentiation of follicular helper T cells remain unclear. Hu and colleagues demonstrate that the transcription factor Foxp1 is critical in inhibiting such differ...

Haikun Wang, Jianlin Geng, **aomin Wen, Enguang Bi, Andrew V Kossenkov… in Nature Immunology (2014)

Article

Developmental stage-specific effects of Pim-1 dysregulation on murine bone marrow B cell development

The serine threonine kinase Pim-1 has documented roles in hematopoietic progenitor and B cell precursor proliferation and survival. Pim-1 is a molecular target of the transcription factor Hoxa9. Previous studi...

Zhihui Xu, Kimberly A. Gwin, Yulin Li, Kay L. Medina in BMC Immunology (2016)

Article

25th Annual Computational Neuroscience Meeting: CNS-2016

A1 Functional advantages of cell-type heterogeneity in neural circuits

Tatyana O. Sharpee, Alain Destexhe, Mitsuo Kawato, Vladislav Sekulić… in BMC Neuroscience (2016)

Article

Abstracts from the 8th International Congress of the Asia Pacific Society of Infection Control (APSIC)

Nantanit Sutthiruk, Mari Botti… in Antimicrobial Resistance & Infection Contr… (2017)

Article

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Chromothripsis is a mutational phenomenon characterized by massive, clustered genomic rearrangements that occurs in cancer and other diseases. Recent studies in selected cancer types have suggested that chromo...

Isidro Cortés-Ciriano, Jake June-Koo Lee, Ruibin **, Dhawal Jain… in Nature Genetics (2020)

Article

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

About half of all cancers have somatic integrations of retrotransposons. Here, to characterize their role in oncogenesis, we analyzed the patterns and mechanisms of somatic retrotransposition in 2,954 cancer g...

Bernardo Rodriguez-Martin, Eva G. Alvarez, Adrian Baez-Ortega… in Nature Genetics (2020)

Article

NQO1 protects obese mice through improvements in glucose and lipid metabolism

Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation...

Andrea Di Francesco, Youngshim Choi, Michel Bernier… in npj Aging and Mechanisms of Disease (2020)

Article

Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice

Stem cells such as mesenchymal stem cells (MSCs) enhance neurological recovery in preclinical stroke models by secreting extracellular vesicles (EVs). Since previous reports have focused on the application of ...

X. Zheng, L. Zhang, Y. Kuang, V. Venkataramani, F. **… in Translational Stroke Research (2021)

Article

A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia

New therapies are urgently needed for Alzheimer’s disease (AD). Sodium oligomannate (GV-971) is a marine-derived oligosaccharide with a novel proposed mechanism of action. The first phase 3 clinical trial of G...

Shifu **ao, Piu Chan, Tao Wang, Zhen Hong, Shuzhen Wang… in Alzheimer's Research & Therapy (2021)