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Comparative effect of chlormadinone acetate and diethylstilbestrol as promoters in mammary tumorigenesis of rats irradiated with γ-rays during lactation
The purpose of this study was to determine the promotional role of estrogen and progestin in the development of radiation-induced mammary tumors. To eliminate the effects of endogenous ovarian hormones on tumo...
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Article
Diabetes Mellitus May Be Associated with Hepatocarcinogenesis in Patients with Chronic Hepatitis C
It is unknown whether diabetes mellitus is a risk factor of the hepatocarcinogenesis in patients with chronic hepatitis C. Three hundred eleven anti-hepatitis C virus (HCV) -positive patients who had undergone...
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Article
Odontoblasts induced from mesenchymal cells of murine dental papillae in three-dimensional cell culture
In an organ culture system under a three-dimensional microenvironment that provides the conditions needed for odontoblast differentiation, a row of odontoblasts can be induced (Kikuchi et al. 1996, 2001). Therefo...
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Article
Rod and Cone a-Waves in Central Retinal Vein Occlusion
To evaluate rod and cone a-waves in cases with unilateral central retinal vein occlusion (CRVO).
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Article
The characteristics of relapse in adult-onset minimal-change nephrotic syndrome
Although minimal-change nephrotic syndrome (MCNS) is highly steroid-responsive, the frequency of relapses in some patients is high, necessitating the administration of repeated courses of prednisolone in high ...
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Article
Tethering by lamin A stabilizes and targets the ING1 tumour suppressor
ING proteins bind to lamin A. ING1 expression and localization is perturbed in lamin A-null cells. Data from Hutchinson-Gilford progeria syndrome (HGPS) cells, which carry mutations in lamin A, suggest that loss ...
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Article
Open AccessModerate alcohol consumption is associated with better endothelial function: a cross sectional study
Moderate alcohol consumption is protective against coronary artery disease. Endothelial dysfunction contributes to atherosclerosis and the pathogenesis of cardiovascular disease. The effects of alcohol consump...
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Article
Prevalence of non-alcoholic fatty liver disease in children and relationship to metabolic syndrome, insulin resistance, and waist circumference
To investigate the prevalence of non-alcoholic fatty liver disease (NAFLD) in children and its relationship to metabolic syndrome, insulin resistance, and waist circumference (WC).
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Article
Pleomorphic adenoma originating from the trachea showing the appearance of a follicular tumor of the thyroid on ultrasonography
Pleomorphic adenoma (PA) is the most common tumor of the salivary gland. This report presents a case of a PA originating from the trachea that looked like a thyroid neoplasm on ultrasonography, showing a well-...
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Article
Bone metabolism after cinacalcet administration in patients with secondary hyperparathyroidism
Cinacalcet, an allosteric modulator of a calcium (Ca)-sensing receptor, significantly suppresses parathyroid hormone (PTH) secretion and bone turnover rate in chronic hemodialysis (HD) patients with secondary ...
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Article
Rituximab in combination with CHOP chemotherapy for the treatment of diffuse large B cell lymphoma in Japan: a retrospective analysis of 1,057 cases from Kyushu Lymphoma Study Group
We performed a retrospective analysis of patients with diffuse large B cell lymphoma treated with rituximab plus CHOP (cyclophosphamide, adriamycin, vincristine and prednisone) as a first-line therapy at 22 ho...
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Article
Open AccessREAP: A two minute cell fractionation method
The translocation or shuttling of proteins between the nucleus and cytoplasm (nucleocytoplasmic transport [NCPT]) is often a rapid event following stimulation with growth factors or in response to stress or ot...
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Article
The development of rare earth element-labelled potassium-depleted clays for use as cohesive sediment tracers in aquatic environments
Understanding the transport behaviour of fine cohesive sediment is fundamental to the sustainable management of aquatic environments. Sediment tracing techniques are widely used for measuring the transport pat...
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Article
Three-dimensional echocardiography findings of biventricular thrombi complicated by cerebral embolism
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Characterisation of non-calcified coronary plaque by 16-slice multidetector computed tomography: comparison with histopathological specimens obtained by directional coronary atherectomy
The efficacy of multidetector computed tomography (MDCT) for assessing coronary plaque composition has not been fully elucidated by comparison with histological findings. This study investigated the efficacy a...
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Article
Löeffler endocarditis and restrictive cardiomyopathy with biventricular apical thrombi
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Article
Acute onset of mediastinal cystic lymphangioma in the puerperium
Lymphangioma is a benign congenital malformation develo** from the prenatal lymphatic vessels. Lymphangiomas are typically slow-growing and asymptomatic, but can occur throughout the body; there are few docu...
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Open AccessA simple protein-energy wasting score for survival prediction of maintenance hemodialysis patients
The nutritional status of patients on maintenance hemodialysis (MHD) is a strong predictor of their survival. We assessed the reliability of a protein-energy wasting (PEW) score as a predictor of the survival ...
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Article
A case of complete clearance of chronic subdural hematoma accompanied by recurrent glioblastoma multiforme after administration of bevacizumab
The efficacy of bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor (VEGF), as an adjuvant therapy against various malignant tumors was recently established. Its pharmacolog...
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Article
Open Accessγ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis
Chronic inflammation-associated bone destruction, which is observed in rheumatoid arthritis (RA) and periodontitis, is mediated by excessive osteoclastogenesis. We showed previously that γ-glutamyltranspeptida...