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Article
Open AccessA prospective study of surgeons’ workloads and associated factors in real-world practice
New technologies such as laparoscopic and robotic surgery are spreading, and there is a demand for physicians to keep up with novel methods. In contrast to the recent focus on healthcare professional burnout, ...
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Article
Open AccessCross-sectional and longitudinal analyses of urinary extracellular vesicle mRNA markers in urothelial bladder cancer patients
We designed this multi-center prospective study with the following objectives: (1) the cross-sectional validation of extracellular vesicles (EV) mRNA markers to detect urothelial bladder cancer (UBC) before tr...
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Article
Low-dose metronomic cisplatin as an antiangiogenic and anti-inflammatory strategy for cancer
Conventional chemotherapy is based on the maximum tolerated dose (MTD) and requires treatment-free intervals to restore normal host cells. MTD chemotherapy may induce angiogenesis or immunosuppressive cell inf...
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Article
Open AccessValidation of the Japanese version of the Body Image Scale for bladder cancer patients
The Body Image Scale (BIS) is a 10-item tool that measures the body images of cancer patients. This study aims to validate the Japanese version of the BIS for bladder cancer patients. A multicenter cross-secti...
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Article
Open AccessObjective evaluation of laparoscopic surgical skills in wet lab training based on motion analysis and machine learning
Our aim was to build a skill assessment system, providing objective feedback to trainees based on the motion metrics of laparoscopic surgical instruments.
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Article
Open AccessPreliminary analysis of the Hayabusa2 samples returned from C-type asteroid Ryugu
C-type asteroids1 are considered to be primitive small Solar System bodies enriched in water and organics, providing clues to the origin and evolution of the Solar System and the building blocks of life. C-type a...
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Chapter and Conference Paper
Spatio-Temporal Characteristics of Energetic Lightning in Southeast Asia: Preliminary Statistical Results
The region of Southeast Asia is known as one of the lightning-prone areas in the world. However, spatial and temporal distributions of high-energy lightning discharges, which cause natural disasters e.g. signi...
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Article
Open AccessSurface environment of Phobos and Phobos simulant UTPS
The Martian Moons eXploration (MMX) mission will study the Martian moons Phobos and Deimos, Mars, and their environments. The mission scenario includes both landing on the surface of Phobos to collect samples ...
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Article
Bacillus Calmette-Guérin-unresponsive non-muscle invasive bladder cancer outcomes in patients without radical cystectomy
Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) is a newly defined subtype that is unlikely to benefit from BCG rechallenge. Radical cystectomy is currently recommended f...
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Article
Open AccessCorrection to: Motion analysis for better understanding of psychomotor skills in laparoscopy: objective assessment-based simulation training using animal organs
This article was updated to correct the labeling of Fig. 6.
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Article
Open AccessMotion analysis for better understanding of psychomotor skills in laparoscopy: objective assessment-based simulation training using animal organs
Our aim was to characterize the motions of multiple laparoscopic surgical instruments among participants with different levels of surgical experience in a series of wet-lab training drills, in which participan...
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Article
Open AccessHealth-related quality of life in Japanese patients with bladder cancer measured by a newly developed Japanese version of the Bladder Cancer Index
We validated a Japanese version of the Bladder Cancer Index (BCI) as a tool for measuring health-related quality of life (HRQOL) in bladder cancer patients treated with various surgical procedures.
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Article
Retroperitoneal extragonadal germ cell tumor without distant metastasis: a case report
A 66-year-old man was referred to our hospital for an incidentally detected 40-mm mass located at the inter-aortocaval area around the renal hilum. Positron emission tomography CT revealed high accumulation (SUVm...
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Article
Open AccessCarbonic anhydrase 2 (CAII) supports tumor blood endothelial cell survival under lactic acidosis in the tumor microenvironment
Tumor endothelial cells (TECs) perform tumor angiogenesis, which is essential for tumor growth and metastasis. Tumor cells produce large amounts of lactic acid from glycolysis; however, the mechanism underlyin...
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Article
Simulation of Stimuli-Responsive and Stoichiometrically Controlled Release Rate of Doxorubicin from Liposomes in Tumor Interstitial Fluid
To simulate the stimuli-responsive and stoichiometrically controlled doxorubicin (DOX) release from liposomes in in vivo tumor interstitial fluid (TIF), the effect of ammonia concentration and pH on the DOX relea...
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Article
Open AccessAn overview of VHF lightning observations by digital interferometry from ISS/JEM-GLIMS
The Global Lightning and sprIte MeasurementS (GLIMS) mission has been conducted at the Exposed Facility of Japanese Experiment Module (JEM-EF) of the International Space Station for more than 30 months. This p...
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Article
Hyperosmolar hyperglycemic nonketotic coma after chemoradiotherapy for esophageal cancer
A 73-year-old man was diagnosed with a type 2 tumor in the middle third of his esophagus by upper esophagogastrointestinal examination and an esophagogram; the tumor was diagnosed as squamous cell carcinoma by...
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Article
Early-stage primary malignant melanoma of the esophagus detected simultaneously with esophageal squamous cell carcinoma
Primary malignant melanoma of the esophagus is a rare disease. The majority of patients are diagnosed at an advanced stage, and only a few are detected at an early stage. We herein describe a case of early-sta...
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Article
Clinical and microbiological evaluation of hemodialysis-associated pneumonia (HDAP): should HDAP be included in healthcare-associated pneumonia?
Although hemodialysis-associated pneumonia (HDAP) was included among the healthcare-associated pneumonias (HCAP) in the 2005 American Thoracic Society (ATS)/Infectious Diseases Society of America (IDSA) guidel...
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Article
Low-Voltage Organic Thin Film Transistors on Flexible Plastic Substrates with Anodized Ta2O5 Gate Insulators
Organic thin film transistors (OTFTs) that operate at low voltage were fabricated using a tantalum oxide (Ta2O5) gate insulator on plastic substrates. The Ta2O5 insulator was prepared by anodizing a Ta gate elect...
