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  1. Article

    Open Access

    Use of thymidine analogues to indicate vascular perfusion in tumours

    Temporary reduction in blood-flow within tumour blood vessels can reduce oxygen supply leading to transient perfusion-limited hypoxia. Consequent selection of cells with mutations and reduced radiosensitivity ...

    A C Begg, I Hofland, I Van Der Pavert, B Van Der Schueren… in British Journal of Cancer (2000)

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  2. Article

    Open Access

    Evaluation of hypoxia in an experimental rat tumour model by [18F]Fluoromisonidazole PET and immunohistochemistry

    This study aimed to evaluate tumour hypoxia by comparing [18F]Fluoromisonidazole uptake measured using positron emission tomography ([18F]FMISO-PET) with immunohistochemical (IHC) staining techniques. Syngeneic r...

    L Dubois, W Landuyt, K Haustermans, P Dupont, G Bormans… in British Journal of Cancer (2004)

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  3. No Access

    Article

    Does 11C-choline PET-CT contribute to multiparametric MRI for prostate cancer localisation?

    The aim of this work was to determine whether 11C-choline positron emission tomography (PET)–computed tomography (CT) makes a positive contribution to multiparametric magnetic resonance imaging (MRI) for localisa...

    L. Van den Bergh, S. Isebaert, M. Koole, R. Oyen… in Strahlentherapie und Onkologie (2013)

  4. Article

    Open Access

    Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial

    This study characterises molecular effect of bevacizumab, and explores the relation of molecular and genetic markers with response to bevacizumab combined with chemoradiotherapy (CRT).

    M Verstraete, A Debucquoy, J Dekervel, J van Pelt, C Verslype… in British Journal of Cancer (2015)

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  5. No Access

    Article

    Comparison of diagnostic accuracy of 111In-pentetreotide SPECT and 68Ga-DOTATOC PET/CT: A lesion-by-lesion analysis in patients with metastatic neuroendocrine tumours

    To compare the diagnostic accuracy of 111In-pentetreotide-scintigraphy with 68Ga-DOTATOC-positron emission tomography (PET)/computed tomography (CT) in patients with metastatic-neuroendocrine tumour (NET) schedul...

    S. Van Binnebeek, B. Vanbilloen, K. Baete, C. Terwinghe, M. Koole… in European Radiology (2016)

  6. No Access

    Article

    The survival impact of neoadjuvant hormonal therapy before radical prostatectomy for treatment of high-risk prostate cancer

    Several randomized controlled trials assessed the outcomes of patients treated with neoadjuvant hormonal therapy (NHT) before radical prostatectomy (RP). The majority of them included mainly low and intermedia...

    L Tosco, A Laenen, A Briganti, P Gontero… in Prostate Cancer and Prostatic Diseases (2017)