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  1. No Access

    Article

    Systematic analysis and validation of differential gene expression in ovarian serous adenocarcinomas and normal ovary

    Cancer of the ovary confers the worst prognosis among women with gynecological malignancies, primarily because most ovarian cancers are diagnosed at late stage. Hence, there is a substantial need to develop ne...

    Dirk Bauerschlag, Karen Bräutigam… in Journal of Cancer Research and Clinical On… (2013)

  2. No Access

    Article

    Salmonella typhimurium engineered to produce CCL21 inhibit tumor growth

    Intravenously-applied bacteria tend to accumulate in tumors and can sporadically lead to tumor regression. Systemic administration of attenuated Salmonella typhimurium is safe and has shown no significant adverse...

    Markus Loeffler, Gaelle Le’Negrate, Maryla Krajewska… in Cancer Immunology, Immunotherapy (2009)

  3. No Access

    Article

    Comparison of pharmacokinetic and metabolic profiling among gossypol, apogossypol and apogossypol hexaacetate

    To characterize the stability, pharmacokinetics and metabolism of analogs of gossypol, apogossypol and apogossypol hexaacetate to provide a basis for comparison.

    Lee Jia, Lori C. Coward, Corenna D. Kerstner-Wood… in Cancer Chemotherapy and Pharmacology (2008)

  4. No Access

    Article

    Bcl-2 Gene Family and Related Proteins in Mammary Gland Involution and Breast Cancer

    The Bcl-2 gene family regulates tissuedevelopment and tissue homeostasis through the interplayof survival and death factors. Family members arecharacterized as either pro-apoptotic or anti-apoptotic, depending...

    Kristel Schorr, Minglin Li… in Journal of Mammary Gland Biology and Neopl… (1999)

  5. No Access

    Article

    Immunochemotherapy of malignant glioma: synergistic activity of CD95 ligand and chemotherapeutics

     Malignant glioma cells are susceptible to CD95(Fas/APO-1)-mediated apoptosis triggered by agonistic antibody. Here we examined the proapoptotic effects of the natural CD95 ligand, a cytotoxic cytokine homolog...

    Wilfried Roth, Adriano Fontana, Martin Trepel… in Cancer Immunology, Immunotherapy (1997)

  6. No Access

    Article

    Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis

     Cytokine-mediated cell death in tumor cells can be achieved through endogenous nitric oxide (NO) from within tumor cells or exogenous NO from either activated macrophages or endothelial cells. The purpose of ...

    Suyun Huang, Yunfang Wang, Pedro J. Beltran… in Cancer Immunology, Immunotherapy (1996)