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Open AccessInhibition of epigenetic and cell cycle-related targets in glioblastoma cell lines reveals that onametostat reduces proliferation and viability in both normoxic and hypoxic conditions
The choice of targeted therapies for treatment of glioblastoma patients is currently limited, and most glioblastoma patients die from the disease recurrence. Thus, systematic studies in simplified model system...
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Open AccessViability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets
Despite the use of multimodal treatment combinations, the prognosis of glioblastoma (GB) is still poor. To prevent rapid tumor recurrence, targeted strategies for the treatment of GB are widely sought. Here, w...
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Article
Prostate Cancer: Biological Dose Considerations and Constraints in Tele- and Brachytherapy