-
Article
Open AccessInsights into treatment of complex Crohn's perianal fistulas
Complex perianal fistula is a common complication of Crohn’s disease (CD) which leads to negative impact on patient’s quality of life. Successful management of the disease requires a multidisciplinary approach...
-
Article
Open AccessResponse to Limited surface impacts of the January 2021 sudden stratospheric warming
-
Article
Open AccessA comparison of covariate adjustment approaches under model misspecification in individually randomized trials
Adjustment for baseline covariates in randomized trials has been shown to lead to gains in power and can protect against chance imbalances in covariates. For continuous covariates, there is a risk that the the...
-
Article
Open AccessDemonstration of high-speed and low-complexity continuous variable quantum key distribution system with local local oscillator
We present an experimental demonstration of the feasibility of the first 20 + Mb/s Gaussian modulated coherent state continuous variable quantum key distribution system with a locally generated local oscillato...
-
Article
Open AccessDiet-induced obesity leads to behavioral indicators of pain preceding structural joint damage in wild-type mice
Obesity is one of the largest modifiable risk factors for the development of musculoskeletal diseases, including intervertebral disc (IVD) degeneration and back pain. Despite the clinical association, no studi...
-
Article
Crohn’s disease in Israeli Jews of Ethiopian heritage—a case series
There is a paucity of information on the prevalence of Crohn’s disease (CD) in patients of African heritage. Israel is home to approximately 144,100 Jews of Ethiopian heritage. We present an audit of six patie...
-
Article
Identifying the Links Among Poverty, Hydroenergy and Water Use Using Data Mining Methods
Water is fundamental to human well-being, social development and the environment. Water development, particularly hydropower, provides an important source of renewable energy. Water development is strongly aff...
-
Article
Open AccessExperimental demonstration of single-shot quantum and classical signal transmission on single wavelength optical pulse
Advances in highly sensitive detection techniques for classical coherent communication systems have reduced the received signal power requirements to a few photons per bit. At this level one can take advantage...
-
Article
Proteotype profiling unmasks a viral signalling network essential for poxvirus assembly and transcriptional competence
To orchestrate context-dependent signalling programmes, poxviruses encode two dual-specificity enzymes, the F10 kinase and the H1 phosphatase. These signalling mediators are essential for poxvirus production, ...
-
Article
Different approaches for Endo-SPONGE® insertion to treat rectal anastomotic leaks
-
Article
A surgical solution to regain bowel continuity following an extended left colectomy—reviving and extending the indication for a “Flip-Flop” procedure
Extended left hemicolectomy might be necessary for several indications. Once the resection is completed, it would be difficult or impossible to anastomose the transverse colon to the rectum due to the difficul...
-
Article
Open AccessOne-year anniversary: The progress of Microsystems & Nanoengineering
-
Article
Absence of 21st century warming on Antarctic Peninsula consistent with natural variability
Here it is shown that the late twentieth century warming trends in the Antarctic Peninsula have ceased, with the Peninsula having instead been cooling for most of the twenty-first century, underscoring the con...
-
Article
Mesenteric root dissection with individualized ileo-colic vessel ligation versus mesenteric pedicle stapling
Numerous factors have been associated with the number of lymph nodes retrieved during laparoscopic colectomy. This study compared the impact of vascular pedicle ligation method on the number of retrieved lymph...
-
Article
Phenological sensitivity to climate across taxa and trophic levels
Differences in phenological responses to climate change among species can desynchronise ecological interactions and thereby threaten ecosystem function. To assess these threats, we must quantify the relative i...
-
Article
Active and passive compliance in an enhanced recovery programme
Enhanced recovery after surgery (ERAS) is a well-established and accepted practice following colorectal surgery and has been demonstrated to reduce hospital length of stay (LOS) and 30-day morbidity. Despite e...
-
Article
Open AccessHandling drop-outs which imply a change of treatment: an evaluation of reference-based imputation
-
Article
Open AccessThe First Engineering Journal from Nature Publishing Group: Microsystems & Nanoengineering
-
Article
The Impact of Anastomotic Leak and Its Treatment on Cancer Recurrence and Survival Following Elective Colorectal Cancer Resection
Anastomotic leakage is a serious complication in restorative colorectal surgery. Anastomotic leakage and its subsequent management may have long-term impact on survival. This study aims to assess the impact of...
-
Article
Predictive factors for perioperative blood transfusions in laparoscopic colorectal surgery
Allogeneic perioperative blood transfusion (PBT) has been associated with higher rates of postoperative complications in patients undergoing colorectal surgery and increased tumor recurrence in cancer patients...
