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Construction of eukaryotic expression vector with granulocyte-macrophage colony-stimulating factor gene

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  1. Article

    Decreased Urinary Epidermal Growth Factor in Children with Acute Renal Failure: Epidermal Growth Factor/Creatinine Ratio Not a Reliable Parameter for Urinary Epidermal Growth Factor Excretion

    To verify some animal experimental results in humans, we have studied urinary epidermal growth factor (EGF) excretion in normal children as well as children with acute renal failure (ARF). Urinary EGF excretio...

    Yong-Kwei Tsau, Ji-Nan Sheu, Chiung-Hui Chen, Ru-Jeng Teng in Pediatric Research (1996)

  2. Article

    Intermediates in Endogenous Synthesis of C22:6ω3 and C20:4ω6 by Term and Preterm Infants

    An alternative pathway of ω3 and ω6 fatty acid metabolism has been described in isolated rat hepatocytes and human fibroblasts. This alternative pathway, which is independent of Δ4 desaturation, involves elongati...

    Thorsten U Sauerwald, David L Hachey, Craig L Jensen, Huiming Chen in Pediatric Research (1997)

  3. Article

    Effect of Short-Term Cigarette Smoke Exposure on Body Weight, Appetite and Brain Neuropeptide Y in Mice

    Although nicotinic receptors have been demonstrated in hypothalamic appetite-regulating areas and nicotine administration alters food intake and body weight in both animals and humans, the mechanisms underlyin...

    Hui Chen, Ross Vlahos, Steve Bozinovski, Jessica Jones in Neuropsychopharmacology (2005)

  4. Article

    Open Access

    A haplotype variation affecting the mitochondrial transportation of hMYH protein could be a risk factor for colorectal cancer in Chinese

    The human MutY homolog (hMYH), a DNA glycolsylase involved in the excision repair of oxidative DNA damage, is currently studied in colorectal cancer (CRC). We previously demonstrated a haplotype variant c.53C>T/c...

    Huimei Chen, Lizhi Xu, Qiufeng Qi, Yanweng Yao, Ming Zhu, Ya** Wang in BMC Cancer (2008)

  5. Article

    Open Access

    An association between hOGG1Ser326Cys polymorphism and the risk of bladder cancer in non-smokers: a meta-analysis

    Bladder cancer results from complex interactions between many genetic and environment factors. The polymorphism Ser326Cys in hOGG1 gene has been reported to be associated with bladder cancer in some studies, thou...

    Changwei Ji, Zhao Liu, Huimei Chen, Hongqian Guo, Changjian Liu in BMC Cancer (2012)

  6. Article

    Open Access

    Use of the PiCCO system in critically ill patients with septic shock and acute respiratory distress syndrome: a study protocol for a randomized controlled trial

    Hemodynamic monitoring is very important in critically ill patients with shock or acute respiratory distress syndrome(ARDS). The PiCCO (Pulse index Contour Continuous Cardiac Output, Pulsion Medical Systems, G...

    Zhongheng Zhang, **ao Xu, Min Yao, Huilan Chen, Hongying Ni, Haozhe Fan in Trials (2013)

  7. Article

    Open Access

    Prevalence and risk factors for diabetic retinopathy in a high-risk Chinese population

    Lifestyle plays an important role in the development of diabetic retinopathy. The lifestyle in Guangzhou is different from other cities in China as the Cantonese prefer eating rice porridge, but not spicy food...

    Jiao Wang, Ru-Yi Zhang, Rong-** Chen, Jia Sun, Rui Yang, **ao-Yun Ke in BMC Public Health (2013)

  8. Article

    Open Access

    Ring cell migration assay identifies distinct effects of extracellular matrix proteins on cancer cell migration

    Alterations in cell migration are a hallmark of cancer cell invasion and metastasis. In vitro assays commonly used to study cell migration, including the scratch wound healing assay, Boyden chamber assay, and new...

    Hui Chen, Josephine Nalbantoglu in BMC Research Notes (2014)

  9. Article

    Open Access

    Nerve growth factor improves functional recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis in rats with spinal cord injury

    Endoplasmic reticulum (ER) stress-induced apoptosis plays a major role in various diseases, including spinal cord injury (SCI). Nerve growth factor (NGF) show neuroprotective effect and improve the recovery of...

    Hongyu Zhang, Fenzan Wu, **aoxia Kong, Jie Yang in Journal of Translational Medicine (2014)

  10. Article

    Open Access

    Simvastatin prevents alveolar bone loss in an experimental rat model of periodontitis after ovariectomy

    Periodontitis is an inflammatory disease characterized by the loss of connective tissue and alveolar bone. There is an increasing evidence that periodontitis is associated with a number of chronic disease, inc...

    **n-chen Xu, Hui Chen, ** Zhang, Zan-**g Zhai in Journal of Translational Medicine (2014)

  11. Article

    Open Access

    Left ventricular filling pressure assessed by exercise TDI was correlated with early HFNEF in patients with non-obstructive hypertrophic cardiomyopathy

    Hypertrophic cardiomyopathy (HCM) patients are more susceptible to suffer from heart failure with normal ejection fraction (HFNEF). Therefore, it is critical to evaluate the relationship between left ventricul...

    Guodong Ma, Ming Xu, Wei Gao, Zhao** Li, Weihong Li in BMC Cardiovascular Disorders (2014)

  12. Article

    Open Access

    miR-130a can predict response to temozolomide in patients with glioblastoma multiforme, independently of O6-methylguanine-DNA methyltransferase

    Currently, O6-methylguanine-DNA methyltransferase(MGMT) promoter methylation is the most convincing predictive biomarker for temozolomide (TMZ) response in patients with glioblastoma multiforme (GBM). However,...

    Huiyuan Chen, **nyi Li, Wenbin Li, Huyong Zheng in Journal of Translational Medicine (2015)

  13. Article

    Open Access

    The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer

    The human genome encodes many long non-coding RNAs (lncRNAs). However, their biological functions, molecular mechanisms, and the prognostic value associated with pancreatic ductal adenocarcinoma (PDAC) remain ...

    Zhihua Li, **aohui Zhao, Yu Zhou, Yimin Liu in Journal of Translational Medicine (2015)

  14. Article

    Open Access

    The changing trends of HIV-1 prevalence and incidence from sentinel surveillance of five sub-populations in Yunnan, China, 2001–2010

    Yunnan is one of the provinces hardest-hit by HIV in China. To understand HIV epidemic dynamics and evaluate prevention effectiveness, we studied the changing trends in HIV-1 prevalence and incidence among fiv...

    Li Yang, Min Chen, Yanling Ma, Hongbing Luo, Chaojun Yang, Yingzhen Su in BMC Public Health (2015)

  15. Article

    Open Access

    Concordance analysis of methylation biomarkers detection in self-collected and physician-collected samples in cervical neoplasm

    Non-attendance at gynecological clinics is a major limitation of cervical cancer screening and self-collection of samples may improve this situation. Although HPV testing of self-collected vaginal samples is a...

    Cheng-Chang Chang, Rui-Lan Huang, Yu-** Liao, Po-Hsuan Su, Yaw-Wen Hsu in BMC Cancer (2015)

  16. Article

    Open Access

    Features of COPD patients by comparing CAT with mMRC: a retrospective, cross-sectional study

    The group assignment of chronic obstructive pulmonary disease (COPD) may differ depending on whether the COPD assessment test (CAT) or modified Medical Research Council dyspnoea scale (mMRC) is used.

    Wei-Chang Huang, Ming-Feng Wu, Hui-Chen Chen in npj Primary Care Respiratory Medicine (2015)

  17. Article

    Open Access

    Argonaute 2 and nasopharyngeal carcinoma: a genetic association study and functional analysis

    Argonaute 2 (AGO2), a central component of RNA-induced silencing complex, plays critical roles in cancer. We examined whether the single nucleotide polymorphisms (SNPs) of AGO2 were related to the risk of nasopha...

    Peiyao Li, **feng Meng, Yun Zhai, Hongxing Zhang, Lixia Yu, Zhifu Wang in BMC Cancer (2015)

  18. Article

    Open Access

    Atorvastatin treatment improves effects of implanted mesenchymal stem cells: meta-analysis of animal models with acute myocardial infarction

    Previous studies reported that Atorvastatin (ATOR) can improve the efficacy of Mesenchymal stem cells (MSCs) transplantation after acute myocardial infarction (AMI). However, the results of those studies were ...

    Guo Dai, Qing Xu, Rong Luo, Jianfang Gao, Hui Chen in BMC Cardiovascular Disorders (2015)

  19. Article

    Erratum: Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database

    Correction to: Molecular Psychiatry advance online publication, 7 April 2015; doi:10.1038/mp.2015.40 Following publication of this paper, the authors noticed that the postal address shown for corresponding aut...

    **chen Li, Tao Cai, Yi Jiang, Huiqian Chen, **n He, Chao Chen in Molecular Psychiatry (2016)

  20. Article

    Open Access

    Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report

    Non-Shiga toxin-associated hemolytic uremic syndrome is known to be caused by dysregulation of the alternative complement pathway. Infections, drugs, pregnancy, bone marrow transplantation, malignancy, and aut...

    Ziqiang Zhu, Hui Chen, Rupinder Gill, Jenchin Wang in Journal of Medical Case Reports (2016)

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