1,013 Result(s)

Article

Relationship of imipenem therapeutic drug monitoring to clinical outcomes in critically ill patients: a retrospective cohort study

The primary objective of this study was to evaluate the predictors associated with target concentration (non-)attainment of imipenem in critically ill patients. The secondary objective was to explore the corre...

Ye**g Wu, Zhangyang Lu, Pei Liang… in Naunyn-Schmiedeberg's Archives of Pharmaco… (2024)

Article

Several families of q-ary cyclic codes with length \(q^m-1\)

It is very hard to construct an infinite family of cyclic codes of rate close to one half whose minimum distances have a good bound. Tang-Ding codes are very interesting, as their minimum distances have a squa...

** Li, Huan Zhu, Shan Huang in Cryptography and Communications (2024)

Article

[¹⁸F]FDG PET-CT radiomics signature to predict pathological complete response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer: a multicenter study

This study aims to develop and validate a radiomics model based on ¹⁸F-fluorodeoxyglucose positron emission tomography–computed tomography ([¹⁸F]FDG PET-CT) images to predict pathological complete response (pCR) ...

Minglei Yang, **aoxiao Li, Chuang Cai, Chunli Liu, Minjie Ma… in European Radiology (2024)

Article

Efficient molecular conformation generation with quantum-inspired algorithm

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown g...

Yunting Li, **aopeng Cui, Zuoheng Zou… in Journal of Molecular Modeling (2024)

Article

ANT2: the first mammalian mitochondrial RNA transport translocon

Huanhuan Zhu, Weiqiang Lin, Aifu Lin in Cell Research (2024)

Article

Targeted protein degradation combined with PET imaging reveals the role of host PD-L1 in determining anti-PD-1 therapy efficacy

Immunohistochemical staining of programmed death-ligand 1 (PD-L1) in tumor biopsies acquired through invasive procedures is routinely employed in clinical practice to identify patients who are most likely to b...

**hong Du, Shu Han, Haoyi Zhou, Jianze Wang… in European Journal of Nuclear Medicine and M… (2024)

Article

K do** stabilizes three-dimensional K_0.2Na_1.3Mn_0.5O_2-d as high-performance cathode for sodium-ion batteries

It is a difficult challenge to simultaneously employ the cationic and anionic redox chemistry in cathode materials for sodium-ion batteries with high energy. Even though layered oxides (classified as two-dimen...

Jia-Hao Xu, You-Huan Zhu, Wei-Min Yang, Hua Cheng, Zhou-Guang Lu in Rare Metals (2024)

Article

The Involvement of Immune Cells Between Ischemic Stroke and Gut Microbiota

Ischemic stroke, a disease with high mortality and disability rate worldwide, currently has no effective treatment. The systemic inflammation response to the ischemic stroke, followed by immunosuppression in f...

Bei Pu, Hua Zhu, Liang Wei, Lijuan Gu, Shenqi Zhang… in Translational Stroke Research (2024)

Article

Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway

The angiotensin II type 2 receptor (AT2R) is a well-established component of the renin-angiotensin system and is known to counteract classical activation of this system and protect against organ damage. Pharma...

Chang-yong Xu, Ji Jiang, Yue An, Peng-fei Ye, Cun-cun Zhang… in Acta Pharmacologica Sinica (2024)

Article

CEUS in prediction of early recurrence of hepatocellular carcinoma after curative resection and to stratify the risk of early recurrence: a retrospective observational study

Early recurrence (ER) after surgery is related to early death in patients with hepatocellular carcinoma (HCC) after radical resection. To explore the role of preoperative contrast-enhanced ultrasound (CEUS) in...

Zhe Huang, Rong-Hua Zhu, Shan-shan Li, Hong-Chang Luo, Kai-Yan Li in Abdominal Radiology (2024)

Article

Enhanced Stability and Solidification of Volatile Eugenol by Cyclodextrin-Metal Organic Framework for Nasal Powder Delivery

Eugenol (Eug) holds potential as a treatment for bacterial rhinosinusitis by nasal powder drug delivery. To stabilization and solidification of volatile Eug, herein, nasal inhalable γ-cyclodextrin metal-organi...

Huajie Zhu, Yuting Lv, Fangyuan **n, Manli Wang, **angyu Zhao… in AAPS PharmSciTech (2024)

Article

Single-cell transcriptome analysis reveals the regulatory functions of islet exocrine cells after short-time obesogenic diet

This study aims to investigate the functions of exocrine islet cell subtypes in the early stage of obesity induced by high-fat diet (HFD), which is accompanied with deterioration of the systemic insulin respon...

Qianqian Sun, Huiyu Tang, Huan Zhu, Yanyan Liu, Min Zhang, Chenghang Che… in Endocrine (2024)