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Open AccessSystem-wide identification of novel de-ubiquitination targets for USP10 in gastric cancer metastasis through multi-omics screening
Ubiquitin-specific peptidase 10 (USP10), a typical de-ubiquitinase, has been found to play a double-edged role in human cancers. Previously, we reported that the expression of USP10 was negatively correlated w...
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Article
The Involvement of Immune Cells Between Ischemic Stroke and Gut Microbiota
Ischemic stroke, a disease with high mortality and disability rate worldwide, currently has no effective treatment. The systemic inflammation response to the ischemic stroke, followed by immunosuppression in f...
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Article
Open AccessIncidence and risk factors of stress urinary incontinence after laparoscopic hysterectomy
To observe the long-term effects of total hysterectomy on urinary function, evaluate the effects of preoperative nutritional status, urinary occult infection, and surgical factors on the induction of postopera...
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Article
ATG5 Knockdown Attenuates Ischemia‒Reperfusion Injury by Reducing Excessive Autophagy-Induced Ferroptosis
Autophagy has been described to be both protective and pathogenic in cerebral ischemia/reperfusion (I/R) injury. The underlying association between autophagy and ferroptosis in ischemic stroke has not yet been...
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Article
Neuroinflammatory Biomarkers in the Brain, Cerebrospinal Fluid, and Blood After Ischemic Stroke
The most frequent type of stroke, known as ischemic stroke (IS), is a significant global public health issue. The pathological process of IS and post-IS episodes has not yet been fully explored, but neuroinfl...
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Article
Open AccessDoes social capital aid in leveling the income gradient in child mental health? A structural analysis of the left-behind and not-left-behind Chinese children
Few prior studies have investigated the income gradient in child mental health from a socio-environmental perspective. In an age when child mental health problems in a rapidly changing social environment have ...
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Article
Semi-clathrate hydrate based carbon dioxide capture and separation techniques
CO2 is considered as the main contributor to global warming, and hydrate enclathration is an efficient way for carbon capture and separation (CCS). Semi-clathrate hydrate (SCH) is a type of clathrate hydrate capa...
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Article
Open AccessDifferent gender-derived gut microbiota influence stroke outcomes by mitigating inflammation
Stroke is associated with high disability and mortality rates and increases the incidence of organ-related complications. Research has revealed that the outcomes and prognosis of stroke are regulated by the st...
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Article
Open AccessDoes social capital interact with economic hardships in influencing older adults’ health? A study from China
The importance of social and economic capital as predictors of health is widely documented, yet the complexity of interactions between them and effects on older people’s health is still unclear. Combining the ...
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Article
Open AccessRelevant mediators involved in and therapies targeting the inflammatory response induced by activation of the NLRP3 inflammasome in ischemic stroke
The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin domain-containing 3 (NLRP3) inflammasome is a member of the NLR family of inherent immune cell sensors. The NLRP3 inflammaso...
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Article
Open AccessExtracellular vesicle-derived miRNA as a novel regulatory system for bi-directional communication in gut-brain-microbiota axis
The gut-brain-microbiota axis (GBMAx) coordinates bidirectional communication between the gut and brain, and is increasingly recognized as playing a central role in physiology and disease. MicroRNAs are import...
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Article
A Remark on Stochastic Flows in a Hilbert Space
This paper is an extension of known results of Pesin’s entropy formula and SRB measures for random compositions of infinite-dimensional map**s to the continuous-time setting of stochastic flows. Consider a s...
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Open AccessBidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
Emerging evidence suggests that gut-brain-microbiota axis (GBMAx) may play a pivotal role linking gastrointestinal and neuronal disease. In this review, we summarize the latest advances in studies of GBMAx in ...
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Article
Open AccessCD4 T cell deficiency attenuates ischemic stroke, inhibits oxidative stress, and enhances Akt/mTOR survival signaling pathways in mice
Inhibition of CD4 T cells reduces stroke-induced infarction by inhibiting neuroinflammation in the ischemic brain in experimental stroke. Nevertheless, little is known about its effects on neuronal survival si...
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Initiation of the inflammatory response after renal ischemia/reperfusion injury during renal transplantation
Ischemia/reperfusion injury (IRI) occurs commonly during renal transplantation. It has been well demonstrated that the inflammatory response has an important role in the pathogenesis and pathological processes...
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Open AccessGlycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms
Glycyrrhizin (Gly) protects against brain injury induced by stroke. We studied whether Gly achieves its protection by inhibiting T cell activity and high-mobility group box 1 (HMGB1) release in the ischemic br...
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Article
USP10 Expression in Normal Adrenal Gland and Various Adrenal Tumors
Ubiquitin-specific protease 10 (USP10), a novel deubiquitinating enzyme, is associated with androgen receptor transcriptional activity and pathological processes of tumor. However, information between USP10 an...
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Article
T Cells and Cerebral Ischemic Stroke
Stroke results in cerebral inflammation that causes brain injury and triggers immunodepression, resulting in an increased incidence of morbidity and mortality secondary to remote infection. It is well known t...
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Article
A Staining Method for Assessing the Viability of Esteya vermicola Conidia
The viability of conidia of Esteya vermicola, a potentially important biocontrol agent against the pinewood nematode Bursaphelenchus xylophilus, is usually determined by cultivation for 18–48 h in culture medium....
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Effect of Nutrition and Environmental Factors on the Endoparasitic Fungus Esteya vermicola, a Biocontrol Agent Against Pine Wilt Disease
The nematophagous fungus Esteya vermicola has tremendous potential for biological control. This species exhibits strong infectious activity against pinewood nematodes, whereas the study on the effect of nutrition...