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Article
Open AccessDigital web-based research map by the German Society of Vascular Surgery (DGG): a tool to increase visibility and awareness of science in vascular surgery and vascular medicine in Germany
The German Society for Vascular Surgery and Vascular Medicine (Deutsche Gesellschaft für Gefäßchirurgie und Gefäßmedizin, DGG) represents over 3100 members. In addition to continuing education and professional po...
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Article
Open AccessSichtbarkeit von Forschung in Deutschland zur Förderung wissenschaftlicher Zusammenarbeit
Die Deutsche Gesellschaft für Gefäßchirurgie und Gefäßmedizin (DGG) hat mit der Einführung der digitalen Forschungslandkarte ein innovatives Projekt realisiert, das einen umfassenden Überblick über Arbeitsgrup...
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Article
Open AccessTargeting GD2 after allogeneic SCT: effector cell composition defines the optimal use of ch14.18 and the bispecific antibody construct NG-CU (GD2-CD3)
We investigated whether T cell-recruiting bispecific anti-CD3/GD2 antibody NG-CU might be an alternative to therapeutic anti-GD2 monoclonal antibody (mAb) ch14.18, mediating complement-dependent cytotoxicity (...
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Article
Aging of electron-written YBCO superconducting thin film structures
The aging of Y1Ba2Cu3O7-δ thin film structures after low energy 30 keV electron irradiation has been investigated. The irradiation was aimed at creating artificial channels with suppressed superconductivity that ...
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Article
Increasing the Transition Temperature of High-TC Superconductor Thin Films by Organic Linking of Gold Nanoparticles
The transition temperature, TC, of two types of optimally doped cuprate high-TC superconductor films, YBa2Cu3O7-δ and La1.85Sr0.15CuO4, is found to increase upon linking Au nanoparticles to their surface via orga...
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Article
Registerdaten sind elementar zu den prospektiv randomisierten Studien
Ziel der vorliegenden Übersicht ist es, anhand der Datenbasis des Deutschen Instituts für Gefäßmedizinische Gesundheitsforschung (DIGG) der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin (DGG) der ...
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Article
POPART – ein Register zur Versorgung des Poplitealarterienaneurysmas
Es sollen erste Ergebnisse des multizentrischen Registers POPART zur Behandlung des Poplitealarterienaneurysmas (PAA) vorgestellt werden.
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Article
Chronisch-kritische Ischämie – Perspektive der Grundlagenforschung
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Article
Open AccessTyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia
The fms-related tyrosine kinase 3 (FLT3) receptor has been extensively studied over the past two decades with regard to oncogenic alterations that do not only serve as prognostic markers but also as therapeuti...
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Article
An Fc-optimized CD133 antibody for induction of NK cell reactivity against myeloid leukemia
Antibody-dependent cellular cytotoxicity (ADCC) of natural killer (NK) cells largely contributes to the success of monoclonal antibody (mAb) treatment in cancer. As no antibodies are clinically available for i...
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Article
Size-dependent magnetism and exchange bias effect in Sm0.27Ca0.73MnO3 nanoparticles
Magnetic properties of compacted Sm0.27Ca0.73MnO3 nanoparticles with average particle size ranging from 20 to 80 nm have been investigated in wide temperature and magnetic field range. It has been found that char...
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Article
Open AccessControlling avalanche criticality in 2D nano arrays
Many physical systems respond to slowly changing external force through avalanches spanning broad range of sizes. Some systems crackle even without apparent external force, such as bursts of neuronal activity ...
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Article
Induktion von Arteriogenese in der Peripherie
Arteriogenese, das Wachstum präformierter Arteriolen zu funktionellen Konduktanzarterien, kann im Tiermodell als experimenteller Grundlage zur Erforschung grundlegender Mechanismen induziert werden. Die für di...
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Article
Arteriogenese
Arteriogenese ist der Umbau von Arteriolen in funktionelle Kollateralgefäße nach Verschluss einer Arterie. Das Verständnis der molekularen Mechanismen des Kollateralwachstums bietet Ansatzpunkte für eine thera...
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Article
Magnetic properties of electron-doped La0.23Ca0.77MnO3 nanoparticles
Magnetic properties of electron-doped La0.23Ca0.77MnO3 manganite nanoparticles, with average size of 12 and 60 nm, prepared by the glycine–nitrate method, have been investigated in the temperature range 5–300 K a...
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Article
Generation, selection and preclinical characterization of an Fc-optimized FLT3 antibody for the treatment of myeloid leukemia
The therapeutic efficacy of humanized or chimeric second-generation antitumor antibodies is clearly established, but often limited. In recent years, defined modifications of the glycosylation pattern or the am...
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Article
Schubspannungsgesteuerte microRNAs in der Arteriogenese
Arteriogenese ist der schubspannungsinduzierte Umbau von präexistenten Kollateralarteriolen zu funktionellen Konduktanzarterien. Mit diesem Prozess kann die Blutversorgung einer Region nach dem Verschluss eine...
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Article
Glassy Behavior of La0.8Ca0.2MnO3 Nanoparticles
Magnetic and transport properties of La0.8Ca0.2MnO3 nanoparticles with average size of 18 nm and Curie temperature T C≈231 K have been studied. Pronounced irreversibility of magnetization ...
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Article
A bispecific single-chain antibody that mediates target cell-restricted, supra-agonistic CD28 stimulation and killing of lymphoma cells
We have previously reported that r28M, a recombinant bispecific single-chain antibody directed to a melanoma-associated proteoglycan (NG2) and the costimulatory CD28 molecule on T cells, induced T-cell activat...
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Article
Analyse der mehrphasigen 64-Zeilen-Multidetektor-Computertomographie zur präoperativen angiographischen Evaluation potenzieller Lebendnierenspender
Die anatomische Darstellung und Erfassung möglicher Anomalien der Nierengefäße und Ureteren ist für die Planung einer Lebendnierenspende von essenzieller Bedeutung. Die vorliegende Untersuchung soll die Wertig...
