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Article
Therapeutic nanoparticles from novel multiblock engineered polyesterurethanes
A novel biodegradable material belonging to the class of polyester-urethanes (PURs), based on poly(ε-caprolactone) (PCL) blocks, was proposed as matrix-forming material for the preparation of nanoparticles by ...
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Article
Processing and characterization of innovative scaffolds for bone tissue engineering
A new protocol, based on a modified replication method, is proposed to obtain bioactive glass scaffolds. The main feature of these samples, named “shell scaffolds”, is their external surface that, like a compa...
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Article
Transglutaminase Reactivity with Gelatine: Perspective Applications in Tissue Engineering
Gelatine was crosslinked by means of an enzymatic treatment using tissue transglutaminase (tTGase) (Sigma) and microbial transglutaminase (mTGase) (A**omoto) which catalyses the formation of isopeptide bonds ...
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Article
Cell response of cultured macrophages, fibroblasts, and co-cultures of Kupffer cells and hepatocytes to particles of short-chain poly[(R)-3-hydroxybutyric acid]
The known biodegradability of poly[(R)-3-hydroxybutyric acid] (PHB) in certain biological environments has lead to its proposed use as biodegradable, biocompatible polymer. Recently, a new, rapidly biodegradable ...
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Article
Phagocytosis and biodegradation of short-chain poly [(R)-3-hydroxybutyric acid] particles in macrophage cell line
The biocompatibility and the degradation mechanisms of block co-polyurethanes containing crystallizable telechelic poly [(R)-3-hydroxybutyric acid] (PHB) segments have found recently growing interest for the poss...