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    Article

    Therapeutic nanoparticles from novel multiblock engineered polyesterurethanes

    A novel biodegradable material belonging to the class of polyester-urethanes (PURs), based on poly(ε-caprolactone) (PCL) blocks, was proposed as matrix-forming material for the preparation of nanoparticles by ...

    C. Mattu, M. Boffito, S. Sartori, E. Ranzato in Journal of Nanoparticle Research (2012)

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    Processing and characterization of innovative scaffolds for bone tissue engineering

    A new protocol, based on a modified replication method, is proposed to obtain bioactive glass scaffolds. The main feature of these samples, named “shell scaffolds”, is their external surface that, like a compa...

    D. Bellucci, F. Chiellini, G. Ciardelli in Journal of Materials Science: Materials in… (2012)

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    Article

    Transglutaminase Reactivity with Gelatine: Perspective Applications in Tissue Engineering

    Gelatine was crosslinked by means of an enzymatic treatment using tissue transglutaminase (tTGase) (Sigma) and microbial transglutaminase (mTGase) (A**omoto) which catalyses the formation of isopeptide bonds ...

    F. Bertoni, N. Barbani, P. Giusti, G. Ciardelli in Biotechnology Letters (2006)

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    Cell response of cultured macrophages, fibroblasts, and co-cultures of Kupffer cells and hepatocytes to particles of short-chain poly[(R)-3-hydroxybutyric acid]

    The known biodegradability of poly[(R)-3-hydroxybutyric acid] (PHB) in certain biological environments has lead to its proposed use as biodegradable, biocompatible polymer. Recently, a new, rapidly biodegradable ...

    B. Saad, G. Ciardelli, S. Matter, M. Welti in Journal of Materials Science: Materials in… (1996)

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    Article

    Phagocytosis and biodegradation of short-chain poly [(R)-3-hydroxybutyric acid] particles in macrophage cell line

    The biocompatibility and the degradation mechanisms of block co-polyurethanes containing crystallizable telechelic poly [(R)-3-hydroxybutyric acid] (PHB) segments have found recently growing interest for the poss...

    G. Ciardelli, B. Saad, T. Hirt, O. Keiser in Journal of Materials Science: Materials in… (1995)