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  1. Article

    Pathogenesis of prion diseases: a progress report

    Almost 20 years have passed since Stanley Prusiner proposed that the agent causing transmissible spongiform encephalopathies consists exclusively of a protein and termed it prion. A mixed balance can be drawn ...

    A Aguzzi, F L Heppner in Cell Death & Differentiation (2000)

  2. Article

    Correction: Corrigendum: Experimental autoimmune encephalomyelitis repressed by microglial paralysis

    Nat. Med. 11, 146–152 (2005) In the original version of this article, Fig. 5b was incorrect. The correct panel appears below.

    F L Heppner, M Greter, D Marino, J Falsig, G Raivich, N Hövelmeyer in Nature Medicine (2005)

  3. No Access

    Article

    An unusual case of a highly progressive supratentorial capillary haemangioblastoma – histopathological considerations

    We describe a case of a rapidly progressive, sporadic, non-von Hippel-Lindau (VHL) disease associated supratentorial capillary haemangioblastoma. Despite the classical histopathological presentation consisting...

    B. Orakcioglu, O. W. Sakowitz, A. Perren, F. L. Heppner in Acta Neurochirurgica (2007)

  4. No Access

    Article

    Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas

    Cells with stem cell properties have been isolated from various areas of the postnatal mammalian brain, most recently from the postnatal mouse cerebellum. We show here that inactivation of the tumor suppressor...

    R Sutter, O Shakhova, H Bhagat, H Behesti, C Sutter, S Penkar, A Santuccione in Oncogene (2010)

  5. No Access

    Article

    Predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance

    The increasing importance of targeting drugs in the treatment of several tumor entities (breast, colon, lung, malignant melanoma (MM), lymphoma, and so on) and the necessity of a companion diagnostic (human ep...

    M Dietel, K Jöhrens, Mv Laffert, M Hummel, H Bläker, B M Müller in Cancer Gene Therapy (2013)

  6. No Access

    Article

    A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance

    In April 2013 our group published a review on predictive molecular pathology in this journal. Although only 2 years have passed many new facts and stimulating developments have happened in diagnostic molecular...

    M Dietel, K Jöhrens, M V Laffert, M Hummel, H Bläker, B M Pfitzner in Cancer Gene Therapy (2015)

  7. Article

    Open Access

    COVID-19: Auswirkungen auf das zentrale und periphere Nervensystem

    Die gesundheitlichen Auswirkungen der Coronavirus-Krankheit 2019 (COVID-19) durch die Infektion von SARS-CoV‑2 (Schweres-Akutes-Respiratorisches–Syndrom-Coronavirus 2) werden mit der Ausbreitung der Pandemie i...

    N. Ritschel, H. Radbruch, C. Herden, N. Schneider, C. Dittmayer, J. Franz in Der Pathologe (2021)